温肺活血方治疗慢性阻塞性肺疾病急性发作期临床疗效观察

Observation of Wenfei Huoxue Decoction in Acute Exacerbations of Chronic Obstructive Pulmonary Disease

目的观察温肺活血方治疗慢性阻塞性肺疾病急性发作(AECOPD)的临床疗效。方法将AECOPD患者80例按随机数字表法随机分为治疗组和对照组,对照组采用西医常规治疗,治疗组在西医常规治疗基础上加用温肺活血方;疗程结束后比较两组临床疗效、肿瘤坏死因子-α(TNF-α)、白介素-6(IL-6),进行肺功能检查和血气分析。结果治疗组总有效率为87.50%,高于对照组的72.50%(P<0.05),治疗后治疗组TNF-α、IL-6、PCO2均低于对照组(P<0.05),PO2、FEV1/FEVC、FEV1高于对照组(P<0.05)。结论温肺活血方能够改善患者临床症状,明显降低患者TNF-α、IL-6水平,临床疗效确切。

Objective： To observe the effect of Wenfei Huoxue Decoction on AECOPD. Methods： 80 cases of AECOPD patients,according to the random number table,randomly divided into the treatment group and the control group. The control group was used the conventional western medicine treatment. The treatment group were treated by routine western medicine treatment and Wenfei Huoxue Decoction. After treatment,some indicators were compared between two groups including the clinical curative effect,the TNF- α and the IL-6. Results： The total effective rate of treatment group was 87.50%,which was higher than that of the control group 72.50%（P〈0.05）. TNF-α,IL-6 and PCO2 in the treatment group after treatment were lower than those in the control group（P〈0.05）. However,the PO2,FEV1/FEVC and FEV1 in the treatment group were higher thant those in the control group（P〈0.05）. Conclusion： Wenfei Huoxue Decociton can improve the clinical symptoms of patients. It can significantly reduced the TNF-α and IL-6.