血清CRP联合cTnI检验在急性心肌梗死诊断中应用探讨

Investigation of Serum CRP Combined with cTnI Test for the Diagnosis of Acute Myocardial Infarction

目的研究分析采用血清CRP联合cTnI检验在急性心肌梗死的临床诊断价值。方法选择该院2012年12月—2013年12月收治的100例急性心肌梗死患者作为研究对象,将所有患者按照发病时间分为A组和B组,A组发病时间为〈4 h,B组发病时间4~8 h,每组各50例。再选择同期接受体检的健康人群50例作为对照组。观察对比三组检测血清CRP和cTnI情况,以及检测血清CRP和cTnI阳性率及联合确诊率情况。结果 B组CRP和cTnI与A组和对照组均差异有统计学意义（P〈0.05）;A组和B组在CRP和cTnI的差异有统计学意义（P〈0.05）,对照组在CRP检测与A组的差异有统计学意义（P〈0.05）,而在cTnI检测的差异无统计学意义（P〉0.05）。B组的CRP和cTnI检测的准确率显著高于A组,差异有统计学意义（P〈0.05）。A组和B组的联合确诊率均为100%。结论对于急性心肌梗死患者采取血清CRP联合cTnI检查能够有效提高检测的准确度,缩短检出时间,为患者的治疗提供宝贵的时间,值得临床推广运用。

Objective To study and analyze the clinical value of serum CRP combined with cTnI test in the diagnosis of acute my- ocardial infarction. Methods 100 cases with acute myocardial infarction admitted in our hospital from 2012 December to 2013 December were selected as the research object. And they were divided into group A and group B in accordance with the time of onset with 50 cases in each. Patients in group A had onset time 〈4h, while patients in group B had onset time of 4~8 h. And 50 healthy people underwent physical examination during the dame period were selected as the control group. The serum CRP and cTuI levels and the positive rate of serum CRP and cTnI levels and the combined diagnosis rate of the three groups were observed and compared. Results There were significant differences in CRP and cTnI levels between group B and group A, group B and the control group （P〈0.05）. The differences in CRP and cTnI levels between group A and group B were statistically significant（P〈0.05）. The difference in CRP level was statistically significant（P〈0.05） while that in cTnI level was not（P〉0.05） between group A and the control group. The accuracy rate of CRP and cTnI detection in group B was significantly higher than that in group A with statisti- cally significant difference （P〈0.05）. The combined diagnosis rate of both group A and group B was 100%. Conclusion For pa- tients with acute myocardial infarction, serum CRP combined with cTnI test can effectively improve the accuracy of detection, shorten the detection time and provide precious time for the treatment of the patients, so it is worthy of clinical application and promotion.