功能性消化不良患者十二指肠嗜酸性细胞表达及其意义

Expression and Significance of Duodenal Eosinophils in Patients with Functional Dyspepsia

功能性消化不良(FD)是指具有上腹痛、上腹灼热感、餐后饱胀、早饱等不适症状,但缺乏引起上述症状的器质性疾病的一组临床综合征。胃肠道嗜酸性细胞(EOS)在抵抗病原体入侵、维持肠上皮细胞稳态等方面发挥重要作用。近年研究表明FD患者十二指肠EOS增多,本文就FD患者十二指肠EOS表达及其意义作一综述。

Functional dyspepsia （FD） is a group of clinical syndromes presented as upper abdominal pain, epigastric burning sensation, postprandial fullness, satiety and other symptoms, but lack of organic disease causing these symptoms. Eosinophils （EOS） in gastrointestinal tract play an important role in preventing pathogen invasion and maintaining intestinal epithelial homeostasis. In recent years, many studies have shown a significant increase of duodenal EOS in patients with FD. This article reviewed the expression and significance of duodenal EOS in patients with FD.