窄带成像技术在头颈部恶性肿瘤中的应用

Application of narrowband imaging in head and neck malignant neoplasm

头颈部恶性肿瘤晚期大多伴有转移和邻近器官的浸润,进而会大大增加肿瘤患者死亡率,影响患者生存质量,因此肿瘤早期发现、诊断和干预是临床工作中亟待解决的问题。内镜检测技术一直是头颈恶性肿瘤的有效检查手段,然而传统的白光成像技术在早期检测黏膜下病变时具有局限性。窄带成像技术(NBI)是一种新型、无创的电子内镜显像技术,它可以清晰地显示早期癌变部位黏膜及黏膜下血管的形态和分布,即上皮内乳头样毛细血管袢(IPCL)。该文针对NBI在头颈恶性肿瘤中的临床应用做一综述,期望能对临床工作有更好的应用价值和指导意义。

The malignant neoplasm in head and neck region increased the mortality as for cervical lymph nodes metastasisand local invasion into the adjacent organs which influence the patient’s quality of life.It is essential to detect and diagnosemalignant tumors as early as possible.Endoscopy is useful for the diagnosis and treatment of cancers derivedfrom the head and neck region.However,a laryngoscope with conventional white light （CWL）has technical limitationsin detecting small or superficial lesions on the mucosa.Narrow band imaging（NBI）,especially combined withmagnifying endoscopy （ME）,is a new non-invasive endoscopic imaging technique,which can clearly show the morphologiccharacteristics and sites of mucosal and submucosal vessels,known as intraepithelial papillary capillary loop（IPCL））.This article is a review of NBI’s clinical application for head and neck malignant tumor.