糖皮质激素早期静脉滴注在喘憋性肺炎儿童中的应用效果

Effect of early intravenous glucocorticoid hormone application in children with asthmatic pneumonia

目的探讨糖皮质激素早期静脉滴注在喘憋性肺炎儿童中的应用效果。方法选取在廊坊市第四人民医院接受诊治的喘憋性肺炎患者120例,按入院顺序分为对照组和研究组,每组60例。对照组患者采用常规治疗,研究组中患者在常规治疗的基础上加用糖皮质激素甲波尼龙3次/d,1.5 mg/kg,静脉滴注,连续治疗5 d。结果研究组中患儿喘憋、呼吸困难及罗音消失时间及患儿住院天数明显低于对照组,差异有统计学意义(P<0.05);研究组中患儿的治愈率和总有效率分别为73.3%和98.3%,明显高于对照组,差异有统计学意义(P<0.05)。结论早期使用糖皮质激素类药物如甲波尼龙静脉滴注治疗儿童喘憋性肺炎可迅速解除患儿呼吸道梗阻,减轻其喘憋,气促等呼吸道症状。

Objective To investigate The effect of early intravenous of glucocorticoid application in children with asthmatic pneumonia. Methods 120 cases of asthmatic pneumonia treated in our hospital were divided into the study group and the control group according to the order in the hospital, 60 cases in each group. The control group was treated with conventional therapy, and patients in the study group were treated with intravenous infusion of glucocorticoid（Jia Bo nylon）3 times daily, 1.5 mg / kg on the basis of conventional therapy for 5 consecutive days. Results Dyspnea and wheezing time and hospitalization time of the study group was significantly lower than those of the control group（P 〈0.05）. The cure rate and the total effective rate in the study group were 73.3% and 98.3%, respectively, and were significantly higher than those in control group（P 〈0.05）. Conclusion The early use of glucocorticoid such asmethyl prednisolone infusion for treatment of children with asthmatic pneumonia can rapidly relieve respiratory tract obstruction,reduce wheezing, shorten the breath and other symptoms of the respiratory tract.