低温等离子射频消融联合双针穿刺臭氧注射治疗腰椎间盘突出症的临床研究

Clinical study of low temperature plasma radiofrequency ablation combined with double needle puncture ozone injection in the treatment of lumbar disc herniation

目的:探讨低温等离子射频消融联合双针穿刺贯通式臭氧注射治疗腰椎间盘突出症的临床治疗效果。方法:60例腰椎间盘突出症患者分为3组(每组20例),A组行低温等离子射频消融治疗,B组行双针穿刺臭氧注射治疗,C组行低温等离子射频消融联合双针穿刺臭氧注射治疗。分别于治疗前、治疗后72h、1个月和3个月进行治疗效果评价。结果:治疗前、治疗后72h、1个月和3个月的视觉模拟评分(VAS)分别为:A组(6.6±1.6)分、(1.6±1.0)分、(2.7±1.0)分和(3.3±1.9)分;B组(6.8±1.4)分、(1.4±0.8)分、(3.0±1.1)分和(3.6±1.7)分;C组(6.8±1.5)分、(1.4±0.9)分、(1.9±1.0)和(2.1±1.3)分。治疗后72h、1个月和3个月的优良率分别为:A组(95%)、(80%)、(70%);B组(100%)、(80%)、(75%);C组(100%)、(95%)、(90%)。C组治疗后1个月、3个月VAS下降值较A组、B组均明显增大,差异有显著性意义(P<0.05);C组治疗后1个月和3个月的优良率明显高于A组和B组,组间比较差异有显著性意义(P<0.05)。各组无明显并发症发生。结论:低温等离子射频消融联合双针穿刺臭氧注射治疗腰椎间盘突出症的疗效优于单纯低温等离子射频或双针穿刺臭氧注射,但其远期疗效尚有待于进一步研究。

Objective： To explore the clinical therapeutic effects of low temperature plasma radiofrequency ablation combined with double needle puncture ozone injection in the treatment of lumbar disc herniation.Method： Sixty patients with lumbar disc herniation were divided into 3 groups（20 each group）： group A（low temperature plasma radiofrequency ablation therapy）, group B（double needle puncture injection of ozone therapy）, group C（combined therapy）. The treatment efficacy was evaluated before treatment, 72 hours after treatment, 1 months and 3 months respectively.Result： Before treatment and 72 h, 1 month and 3 months after treatment the VAS scores were： in group A（6.6±1.6）,（1.6±1.0）,（2.7±1.0） and（3.3±1.9）; in group B（6.8±1.4）,（1.4±0.8）,（3.0±1.1） and（3.6±1.7）; in group C（6.8±1.5）,（1.4±0.9）,（1.9±1.0） and（2.1±1.3） respectively. At 72 h, 1 month and 3 months after treatment, the excellent and good rate were： in group A（95%）,（80%）,（70%）; in group B（100%）,（80%）,（75%）; in group C（100%）,（95%）,（90%） respectively. In group C 1 month and 3 months after treatment, the VAS decreased more than that in group A and group B, the difference was statistically significant（P〈0.05）; in group C 1and 3 months after treatment, the excellent and good rate were significantly higher than those in group A andgroup B,there were significant difference between groups（P〈0.05）. Each group had no obvious complications.Conclusion：The low temperature plasma radiofrequency ablation combined with double needle puncture ozone injection in the treatment of lumbar disc herniation was better than that of low temperature plasma radiofrequency ablation therapy or double needle puncture ozone injection,but its long- term effect still need further study.