阿尔茨海默病:从临床诊断标准到神经病理诊断标准的进展和重塑
被引量:4
摘要
阿尔茨海默病(Alzheimer disease,AD)是一种起病隐匿的神经变性疾病,为老年期痴呆最常见的类型。随着科学研究的进展,对AD的认识也有了显著进展,其临床表现与潜在病理变化的关联并不如传统观点所认为的那样密切。
出处
《内科理论与实践》
2015年第2期131-134,共4页
Journal of Internal Medicine Concepts & Practice
参考文献27
-
1McKhann G, Drachman D, Folstein M, et al. Clinical di- agnosis of Alzheimer's disease: report of the NINCDS- ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease[J]. Neurology, 1984, 34(7): 939-944.
-
2Knopman DS, DeKosky ST, Cummings JL, et al. Practice parameter, diagnosis of dementia (an evidence-based re- view)[J]. Neurology, 2001, 56(9): 1143-1153.
-
3McKhann GM, Knopman DS, Chertkow H, et al. The di- agnosis of dementia due to Alzheimer's disease: recom- mendations from the National Institute on Aging- Alzheimer's Association workgroups on diagnostic guide- lines for Alzheimer's disease[J]. Alzheimers Dement, 2011, 7(3): 263-269.
-
4Albert MS, DeKosky ST, Dickson D, et al. The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging- Alzheimer's Association workgroups on diagnostic guide- lines for Alzheimer's disease[J]. Alzheimers Dement, 2011, 7(3): 270-279.
-
5Speding RA, Aisen PS, Beekett LA, et al. Toward defin- ing the preelinical stages of Alzheimer's disease: recom- mendations from the National Institute on Aging- Alzheimer's Association workgroups on diagnostic guide- lines for Alzheimer's disease[J]. Alzheimers Dement, 2011, 7(3): 280-292.
-
6Jack CR Jr, Albert MS, Knopman DS, et al. Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease[J]. Alzheimers Dement, 2011, 7(3): 257-262.
-
7Hyman BT, Trojanowski JQ. Consensus recommendations for the postmortem diagnosis of Alzheimer disease from the National Institute on Aging and the Reagan Institute working group on diagnostic criteria for the neuropatho- logical assessment of Alzheimer disease[J]. J Neuropathol Exp Neurol, 1997, 56(10): 1095-1097.
-
8Hyman BT, Phelps CH, Beach TG, et al. National Insti- tute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease [J]. Alzheimers Dement, 2012, 8(1): 1-13.
-
9Braak H, Del Tredici K. The pathological process under- lying Alzheimer's disease in individuals under thirty [J]. Acta Neuropathol, 2011, 121(2): 171-181.
-
10Braak H, Braak E. Neuropathological stageing of Alzheimer-related changes[J]. Acta Neuropathol, 1991, 82(4): 239-259.
同被引文献45
-
1Jia J, Zhou A, Wei C, Jia X, Wang F, Li F, Wu X, Mok V, Gauthier S, Tang M, Chu L, Zhou Y, Zhou C, Cui Y, Wang Q, Wang W, Yin P, Hu N, Zuo X, Song H, Qin W, Wu L, Li D, Jia L, Song J, Han Y, Xing Y, Yang P, Li Y, Qiao Y, Tang Y, Lv J, Dong X. The prevalence of mild cognitive impairment and its etiological subtypes in elderly Chinese. Alzheimers Dement, 2014, 10:439-447.
-
2Jia J, Wang F, Wei C, Zhou A, Jia X, Li F, Tang M, Chu L, Zhou Y, Zhou C, Cui Y, Wang Q, Wang W, Yin P, Hu N, Zuo X, Song H, Qin W, Wu L, Li D, Jia L, Song J, Han Y, Xing Y, Yang P, Li Y, Qiao Y, Tang Y, Lv J, Dong X. The prevalence of dementia in urban and rural areas of China. Alzheimers Dement, 2014, 10:1-9.
-
3Bai B, Hales CM, Chen PC, Gozal Y, Dammer EB, Fritz JJ, Wang X, Xia Q, Duong DM, Street C, Cantero G, Cheng D, Jones DR, Wu Z, Li Y, Diner 1, Heilman CJ, Rees HD, Wu H, Lin L, Szulwaeh KE, Gearing M, Mufson EJ, Bennett DA, Montine TJ, Seyfried NT, Wingo TS, Sun YE, Jin P, Hanfeh J, Willcock DM, Levey A, Lah JJ, Peng J. U1 small nuclear ribonueleoprotein complex and RNA splicing alterations in Alzheimer's disease. Proc Natl Acad Sci USA, 2013, 110:16562- 16567.
-
4Zhang Z, Song M, Liu X, Kang SS, Kwon IS, Duong DM, Seyfried NT, Hu WT, Liu Z, Wang JZ, (2heng L, Sun YE, Yu SP, Levey AI, Ye K. Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease. Nat Med, 2014, 20:1254-1262.
-
5Castello MA, Soriano S. On the origin of Alzheimer's disease: trials and tribulations of the amyloid hypothesis. Ageing Res Rev, 2014, 13:10-12.
-
6Lin S, Lin Y, Nery JR, Urich MA, Breschi A, Davis CA, Dobin A, Zaleski G, Beer MA, Chapman WC, Gingeras TR, Ecker JR, Snyder MP. Comparison of the transcriptional landscapes between human and mouse tissues. Proc Natl Acad Sei USA, 2014. 111:17224-17229.
-
7张永芳.动物认知功能相关行为学检测实验//王刚.痴呆及认知障碍神经心理测评量表手册.北京:科学出版社,2014:78-86.
-
8Epis R, Gardoni F, Marcello E, Genazzani A, Canonico PL, Di Luca M. Searching for new animal models of Alzheimer's disease. Eur J Pharmacol, 2010, 626:57-63.
-
9Omachi Y, Ito K, Arima K, Matsuda H, Nakata Y, Sakata M, Sato N, Nakagome K, Motohashi N. Clinical impact of HC-PiB PET carried out in addition to MRI and SPECT on the diagnosis of Alzheimer's disease in patients with dementia and mild cognitive impairment. Psychiatry Clin Neurosci, 2015. [Epub ahead of print].
-
10Ritchie CW, Terrera GM, Quinn TJ. Dementia trials and dementia tribulations: methodological and analytical challenges in dementia research. Alzheimers Res Ther, 2015, 7:31.
引证文献4
-
1陈生弟,王刚.痴呆及相关认知功能障碍研究的挑战与展望:停滞中的前行[J].中国现代神经疾病杂志,2015,15(7):512-513. 被引量:4
-
2李斌,孙中莉,陈冠儒,郑育卿,何小静,李桂梅,杨榕,邹思政,陈力文.远志散对东莨菪碱致记忆获得性障碍模型小鼠行为学和脑内AchE活性的影响[J].广州中医药大学学报,2017,34(5):733-736. 被引量:16
-
3王永锋,徐重洋.阿尔茨海默病与轻度认知障碍患者的头颅CT对比观察[J].中国医刊,2018,53(6):650-652. 被引量:5
-
4陀晓宇,李超,郭丽萍,赵华君.尿AD7c-NTP与P300检查在AD源性MCI诊断的价值[J].昆明医科大学学报,2023,44(4):62-68. 被引量:1
二级引证文献26
-
1杨悦,谢文婷,魏涛华,郝文杰,陈娜,钱南南,杨文明.中药石菖蒲防治阿尔茨海默病研究进展[J].辽宁中医药大学学报,2021,23(9):168-172. 被引量:8
-
2刘海,陈士新,许华,王丰.阿尔茨海默病脑血流灌注、海马体积与认知功能相关性分析[J].临床军医杂志,2022,50(3):289-291. 被引量:2
-
3钟伶,林晓华,林丹红.中西医认知功能障碍康复术语框架构建探讨[J].中医杂志,2016,57(14):1181-1184. 被引量:4
-
4邹扬,陈美蓉,任汝静,王刚.认知功能障碍患者病前智力评价[J].中国现代神经疾病杂志,2016,16(9):636-639. 被引量:2
-
5李斌,郭静,王智超,吴雨潇,杨榕,郭宇,文跃强.痰浊阻窍AD大鼠“痰-火-虚”证候演变实验研究[J].辽宁中医药大学学报,2018,20(8):36-39. 被引量:3
-
6陈丽琴.家庭互助教育联合动态评估护理干预对老年认知障碍患者的影响[J].中外女性健康研究,2019(2):13-14. 被引量:2
-
7李桂梅,曾庆荣,王雷,何小静,朱宇溪,李斌.立足慢性复杂性疾病及“脑络-玄府-神机”浅议老年性痴呆[J].中医药导报,2019,25(9):28-31. 被引量:9
-
8阿依江·哈拜克,木卡德斯·哈力克,帕丽达·阿不力孜.阿里红多糖对APP/PS1双转基因小鼠神经损伤的保护作用[J].中药药理与临床,2019,35(3):59-66. 被引量:6
-
9郝彦伟,李斌,张怡,谢沛俊,喻俊榕,向劲松,龚道银.基于脑肠肽Ghrelin水平探讨远志散对AD大鼠学习记忆能力及进食量的影响[J].中国实验方剂学杂志,2020,26(21):8-14. 被引量:15
-
10谢沛俊,郝彦伟,郭静,喻俊榕,李斌.基于PI3K/AKT/GSK-3β通路探讨远志散调控阿尔兹海默病大鼠tau蛋白磷酸化的研究[J].中华中医药学刊,2020,38(11):167-170. 被引量:23
-
1黄俊.帕金森病的研究进展[J].中国当代医药,2010,17(34):15-16. 被引量:8
-
2易秋维(综述),肖农(审校).Duchenne型肌营养不良的治疗进展[J].国际儿科学杂志,2013,40(3):223-226. 被引量:3
-
3袁栋才,刘秀丽,王晓莉,郭力.脑出血的病理与临床进展[J].医学综述,2006,12(10):633-635. 被引量:9
-
4彭六生,李成仁.RNA干扰与神经退行性疾病的研究进展[J].西部医学,2009,21(10):1806-1808. 被引量:1
-
5熊念,孙圣刚.帕金森病运动并发症发生机制的研究进展[J].中国现代神经疾病杂志,2013,13(8):656-662. 被引量:23
-
6史之峰,胡杰,江澄川.胚胎干细胞移植治疗帕金森病的研究进展[J].立体定向和功能性神经外科杂志,2010,23(3):181-184.
-
7车艳艳,向军,张春燕.中药抗脑缺血再灌注损伤的实验研究概况[J].中国康复,2007,22(6):433-434. 被引量:9
-
8周夷,陈生弟,王刚.血纤蛋白原在阿尔茨海默病发病中的作用[J].内科理论与实践,2014,9(5):362-364. 被引量:1
-
9井上聖啓,曲娟.周围神经疾病[J].日本医学介绍,2005,26(12):556-558.
-
10袁建平.脑出血目前治疗的争议现状[J].中国社区医师(医学专业),2009,11(4):3-4.