百草枯致眼化学伤15例分析

Clinical analysis of 15 cases of paraquat-induced ocular chemical injury

目的探讨百草枯（Paraquat）致眼化学伤的临床表现和治疗方法。方法对2012年7月至2014年6月百草枯致眼化学伤15例（21眼）进行回顾性分析。结果百草枯所致眼损伤均出现特征性的结膜伪膜，立即给以结膜囊冲洗，抗生素滴眼液和自体血清滴眼，全身糖皮质激素应用联合伪膜撕除。除1例穹隆部发生睑球粘连外，其余均恢复良好。结论百草枯致眼化学伤典型临床特征为结膜伪膜，患者应及时救治。采用上述治疗方案，效果良好。

Objective To investigate the clinical manifestation and therapeutic method of paraquat-induced ocular chemical injury. Methods A retrospective analysis was conducted on the clinical data of 21 eyes from 15 patients with paraquat-induced ocular chemical injury from July 2012 to June 2014. Results Specific pseudomembranous conjunctivitis was manifested on all patients. The treatment with rinsir^g conjunctival sac, antibiotic eye drops and autologous serum eye drops, as well as systematically injection with glucocorticoid were used combined with pseudomembrane removal. All patients were recovered well except symblepharon occurred on the zone of the fornix in one patient. Conclusion The specific clinical manifestation of paraquat-induced ocular chemical injury is conjunctival pseudomembrane. Those patients should to be rescued timely with the methods given above and they will recover well.