实时组织弹性成像在妊娠期宫颈评价中的应用

The Application of Real-time Tissue Elastography in Evaluating Cervical Maturity during Pregnancy

目的:研究超声实时组织弹性成像技术在妊娠期宫颈成熟度评价中的应用。方法:选取2013年2月—10月在天津市中心妇产科医院进行超声检查的妊娠妇女145例,根据孕周分为3组。所有妊娠妇女在常规产科超声检查后自愿行经阴道超声进行宫颈评价,在二维超声成像基础上测量宫颈长度,之后进行实时组织弹性成像,获得早、中、晚期妊娠时宫颈感兴趣区弹性应变率。结果:各妊娠组间宫颈长度以及宫颈感兴趣区弹性应变率差异均有统计学意义(P<0.05),且早、中期妊娠组宫颈长度大于晚期妊娠组,宫颈感兴趣区弹性应变率小于晚期妊娠组,差异有统计学意义(P<0.05),而早期与中期妊娠组间差异无统计学意义(P>0.05)。宫颈长度与弹性应变率间呈负相关(r=-0.95,P=0.032)。结论:超声实时组织弹性成像技术在妊娠期宫颈成熟度评价中发挥了重要的作用,为临床提供了宫颈成熟度检查的客观指标,并为预测早产开辟了一条新的检查途径。

Objective： To study the ultrasound real-time tissue elastography technique used in the evaluation of cervical maturity during pregnancy. Methods：145 pregnant women were divided into 3 groups according to the gestational weeks. All pregnant women in the routine obstetric ultrasound examination were voluntary to take transvaginal ultrasound cervical evaluation. Cervical length was measured based on two-dimensional ultrasound image,followed by real-time tissue elastography,and then strain rate in the cervical region of interest was gotten during early,mid and late pregnancy. Results：Cervical length and cervical defined region of interest differ at each pregnancy group had statistical significance（P〈0.05）,and the early and mid pregnancy group of cervical length is longer than the third trimester group, cervical defined region of interest differ is less than the late pregnancy group, the difference was statistically significant（P〈0.05）, while there was no statistically significant difference between the early and mid pregnancy group（P〉0.05）. The cervical length was negatively correlation with the strain rate（r=-0.95,P=0.032）. Conclusions：Ultrasound real-time tissue elastography technology during pregnancy plays an important role in cervical maturity evaluation,and it provides accurate index about the cervical maturity.Also, it offers a new examination way to predict premature.