摘要
代谢综合征的发生是复杂的遗传与环境因素相互作用的结果。其发病机制尚未完全明确,近年研究发现适应性免疫及固有性免疫介导的炎症反应机制在代谢综合征的发生、发展中起一定的作用,不同亚群的淋巴细胞及其细胞因子参与代谢综合征组分的发生与发展,其中Th17细胞及调节性T细胞与代谢综合征的关系已受到关注,并取得了一定的研究成果,开辟了代谢综合征的免疫治疗这个全新的领域。
The metabolic syndrome is the result of a complex interaction of genetic and environmental factors. Its pathogenesis remains poorly understood,recent studies have found that adaptive immunity and innate immune-mediated inflammatory mechanisms played a certain role in the development of the metabolic syndrome. Different subsets of lymphocytes and cytokines,different subsets of lymphocytes and cytokines especially Th17 cells and regulatory T cells,are involved in the origin and development of the components of the metabolic syndrome,which opened up a new field of immune treatment of metabolic syndrome.
出处
《医学综述》
2015年第12期2223-2225,2228,共4页
Medical Recapitulate
基金
新疆维吾尔自治区自然科学基金(2012211A096)
