摘要
目的了解宁夏地区朝觐人员乙型肝炎基因分布特点,为探讨宁夏地区朝觐人员乙肝流行趋势提供科学依据。方法采用ELISA法对宁夏地区2010至2012后采用荧光PCR检测方法,对乙肝病毒感染者进行基因分型。结果 90例乙型肝炎HBs Ag阳性者HBV DNA经荧光PCR方法分型,B型5例(5.56%),C型82例(91.11%),其他型3例(3.33%),经统计学分析不同基因型分布有统计学意义;HBV DNA基因型在性别中分布无差异,因此,认为性别与乙肝基因型不具有相关性。结论宁夏地区朝觐人员乙型肝炎患者HBV基因型分布基本符合我国北方的分布特点,以C型为主。
Objective This paper aims to understand the distribution of hepatitis B gene characteristics among pilgrimage in Ningxia area,and provide scientific basis for the study of hepatitis B virus epidemic trend among pilgrims in Ningxia. Methods ELISA method is used in the surface antigen（ HBs Ag） detection among pilgrimage in Ningxia area from 2010 to 2012. The random sample of HBs Ag positive serum is detected with the FQ- PCR method to test the hepatitis B virus genotypes. Results Among the 90 cases of HBs Ag positive HBV DNA tested by FQ- PCR,type B is 5 cases（ 5. 56%）,type C is 82 cases（ 91. 11%）,the other is 3 cases（ 3. 33%）. The statistical analysis of different genotype distribution is of statistical importance; HBV DNA genotype distribution shows no difference in different gender,so the gender and HBV genotype is not relevant. Conclusion HBV genotype is dominated by C type among the pilgrimages at Ningxia,which is consistent with the distribution characteristics in North China.
出处
《口岸卫生控制》
2015年第3期54-55,共2页
Port Health Control
