受血者输血前传染病标志物检测的意义

Significance of detection of infectious markers before blood transfusion

目的:输血前检测受血者传染病标志物,明确临床诊断,避免因输血造成的医疗纠纷。方法:输血前采用酶联免疫吸附实验(ELISA)法对受血者进行乙型肝炎表面抗原(HBs Ag)、丙型肝炎病毒抗体(Anti-HCV)、梅毒螺旋体抗体(Anti-TP)和人类免疫缺陷病毒抗体(Anti-HIV)检测。结果:1传染病标志物总阳性率为13.59%;2HBs Ag阳性率为11.97%,Anti-HCV阳性率为0.41%,Anti-TP阳性率为1.12%,Anti-HIV阳性率为0.10%;3男性HBs Ag阳性率高于女性,差异有统计学意义(P<0.05),男性、女性Anti-HCV阳性率和Anti-TP阳性率差异无统计学意义(P>0.05);4986例受血者中混合感染2例。结论:通过对传染病标志物检测,有利于患者的治疗,避免因输血造成的医疗纠纷,同时防止交叉感染。进一步加强了输血管理,保证输血安全。

Objective： To detect infectious markers of blood recipients before blood transfusion, make clear diag-nosis and avoid medical disputes caused by blood transfusion. Methods：HBsAg, anti-HCV, anti-TP, and anti-HIV were detected by ELISA method. Results：①The total positive rate of infectious markers was 13.59%.②The positive rates of HBsAg, anti-HCV, anti-TP, and anti-HIV were respectively 11.97%, 0.41%, 1.12% and 0.10%. ③The positive rate of HBsAg in male is higher than female, the difference was statistically significant （P〈0.05）. There was no significant difference of the positive rate of anti-HCV between male and female. Also there was no significant difference of the positive rate of anti-TP between male and female.④Two mixed infection cases in blood recipients. Conclusion：Detection of infectious markers is conductive to the treatment of patients;effectively prevent medical dis-putes caused by blood transfusion.