原发性气管支气管淀粉样变1例及文献复习

Primary Tracheobronchial Amyloidosis:Report of One Case and Review of literature

目的:探讨原发性气管支气管淀粉样变的流行病学特征、临床表现及诊断和治疗方法。方法:回顾1例原发性气管支气管淀粉样变病例的临床特点,并结合文献进行分析。结果:患者主要表现为咳嗽、咳痰、咯血及呼吸困难,经纤支镜活检标本刚果红染色阳性。经治疗后患者症状明显缓解。结论:原发性气管支气管淀粉样变临床上发病率极低,容易误诊,组织病理学检查是气管支气管淀粉样诊断的金标准,目前缺乏特异性治疗方法。

Objective： To study the epidemiology, diagnosis and treatment of primary tracheobronchial amyloidosis. Methods： The clinical features of one case of primary tracheobronchial amyloidosis was summarized and the analysis was performed by reviewing the literature. Results： The com- mon symptoms of primary tracheobronchial and pulmonary amyloidosis were cough and sputum, duspnea emtpysis and dyspnea. Biopsy＇s specimens showed that Congored stain was all positive. The patient improved markedly. Conclusion： Primary tracheobronchial amyloidosis is rarely seen, and is apt to be misdiagnosed. Histopathological examination is golden standard for tracheobron- chial amyloidosis diagnosis, but currently there is no specific treatment for it.