基于特征频带磁感应相移谱检测家兔脑出血的实验研究

Experimental Detection Study on Cerebral Hemorrhage in Rabbits Based on Magnetic Induction Phase Shift Spectroscopy Under the Feature Band

本研究目的是提高脑出血磁感应相移检测系统的灵敏度。采用基于特征频带磁感应相移谱的检测方法,对通过自体血注入法建立脑出血的13只家兔进行实验研究,获得了65组相移谱数据,然后根据特征频带下脑出血相移谱的特点设计用于判断脑出血严重程度的B-F分布图。结果显示特征频带内兔脑相位差随出血量增加而增大,出血量3mL时相位差可达-7.750 3°±1.420 4°;B-F分布图能有效地判别脑出血严重程度。本研究显示基于特征频带磁感应相移谱的检测方法将脑出血磁感应检测的灵敏度提高了一个数量级。

This study was aimed to improve the sensitivity of magnetic induction phase shift detection system for cerebral hemorrhage.In the study,a cerebral hemorrhage model with 13 rabbits was established by injection of autologous blood and the cerebral hemorrhage was detected by utilizing magnetic induction phase shift spectroscopy（MIPSS）detection method under the feature band.Sixty five groups of phase shift spectroscopy data were obtained.According to the characteristics of cerebral hemorrhage phase shift spectroscopy under the feature band,an effective method,B-F distribution,to diagnose the severity of cerebral hemorrhage was designed.The results showed that using MIPSS detection method under feature band,the phase shift obviously growed with increase of injection volume of autologous blood,and the phase shift induced by a 3-mL injection reached-7.750 3°±1.420 4°.B-Fdistribution could effectively diagnose the severity of cerebral hemorrhage.It can be concluded that the sensitivity of the cerebral hemorrhage magnetic induction detection system is improved by one order of magnitude with the MIPSS detection method under the feature band.