微流体技术在低温保存领域的研究进展

Research Progress of Application of Microfluidics Techniques in Cryopreservation

微流体技术可能是解决低温保存过程中所遇到问题的一种有效方法。本文详细综述了微流体技术在细胞膜渗透性、保护剂添加与去除、生物材料玻璃化保存三方面的研究进展,总结了在低温保存领域应用微流体技术仍可能存在的问题,并指出了未来的研究方向。

Microfluidics technology may be an effective method to solve some problems in cryopreservation. This re- view presents the research progress of microfluidics technology in the field of cell membrane transport properties, cryoprotectant addition and washout and the vitrification for cryopreservation of biological materials. Existing problems of microfluidics technology in the application of cryopreservation are summarized and future research directions are indicated as well.