薄荷复方煎液对龋病、牙周病致病菌杀菌作用的研究

Analysis of the sterilization effects of Menthol compound decoction on the cariogenic and periodontopathic bacteria

目的:研究薄荷复方煎液对龋病、牙周病致病菌的抑制和杀灭作用。方法:致龋菌血链球菌、变形链球菌和牙周病致病菌牙龈卟啉单胞菌分离培养,将薄荷复方煎液配成不同浓度,分别对4种细菌做药敏试验,记录各自的最小抑菌浓度(MIC)和最小杀菌浓度(MBC)。结果:血链球菌MIC1:32,变形链球菌MIC1:4,牙龈卟啉单胞菌MIC1:32;血链球菌MBC1:16,变形链球菌MBC1:1,牙龈卟啉单胞菌MBC1:8。结论:薄荷复方煎液对龋病、牙周病致病菌有抑制和杀灭作用。

Objective：TO examine the inhibitory and killing effects of Menthol compound decoction on the cariogenic and periodontopathic bacteria,providing the basis for drugs that treat dental caries and periodontal disease. Method：The minimal inhibitory concentration （MIC） and minimal bactericidal concentration （MBC） of Menthol compound decoction a-gainst S. sanguinis （ATCC 10556）,S.mutans （ATCC 25175） and P. gingivalis （ATCC 33277）were measured. Result：The MIC of Menthol compound decoction on S. sanguinis was 1：32,the MBC was 1：16;the MIC of it on S.mutans was 1：4,the MBC was 1：1;the MIC of it on P. gingivalis was 1：32,the MBC was 1：8. Conclusion：Menthol compound decoction has in-hibition and bactericidal effects on oral pathogens.