老年支气管哮喘患者疾病控制与抑郁情绪的相关性研究

Correlation Research of Disease Control and Depressive Emotion in Elderly Patients with Bronchial Asthma

目的探讨支气管哮喘老年患者疾病控制和抑郁、焦虑状态的相互关系。方法入选2012年1月~2014年1月于我院就诊的支气管哮喘老年患者144例作为研究观察对象,同期选取健康对照组144例作为对照1组,选取青中年支气管哮喘患者144例作为对照2组,观察三组患者哮喘控制情况与焦虑、抑郁状态的关系。结果老年支气管哮喘组SAS和SDS评分分别为（42.7±7.5）分、（45.7±9.1）分,均明显高于健康对照组的（31.2±6.8）分、（38.4±6.4）分以及青中年支气管哮喘患者的（35.4±5.8）分、（40.2±9.7）分,差异具有显著性,P〈0.05;且观察组存在焦虑、抑郁的比例为60.42%,明显高于对照1组和2组的14.58%、16.67%,P〈0.05;控制程度越高则SAS和SDS评分越低,P〈0.05;观察组患者中焦虑状态患者30例（20.8%）,抑郁状态患者52例（36.1%）,无焦虑/抑郁状态患者ACT评分明显高于焦虑、抑郁状态患者;应用关联性分析结果显示,ACT评分与SAS和SDS评分呈负相关,r=-0.51/-0.19,t=-7.22/-3.18,差异均具有显著性,P〈0.05。结论老年支气管哮喘对比青中年支气管哮喘患者更易出现焦虑、抑郁状态,而对比同年龄段的健康人群也更容易出现焦虑、抑郁情绪,其程度与哮喘控制效果有密切关系,焦虑、抑郁程度越高,其哮喘控制的效果也就越差。

Objective To study the correlation of disease control and depression or anxiety state in elderly patients with bronchial asthma. Method 144 elderly patients with bronchial asthma treated from January 2012 to January 2014 in our hospital were selected as observation group; 144 healthy check- ups were selected as group one; 144 young and middle- aged patients with bronchial asthma were selected as group two. the anxiety and depression state of three groups were investigated with SAS and SDS,and discussed; through ACT,the control degree of observation group was analyzed; the control degree,correlation with anxiety depression state,scores of anxiety depression at different levels were discussed. Result SAS and SDS scores of observation group were significantly higher than those of Group 1（ P〈0. 05）; SAS and SDS scores of observation group were significantly higher than those of group two（ P〈0. 05）; the higher the control degree was,the lower SAS and SDS scores were（ P〈0. 05）. The observation group had 30 cases with anxiety（ 20. 8%） and 52 cases with depression（ 36. 1%）. ACT scores for patients without anxiety / depression were significantly higher than those of patients with anxiety / depression.Through correlation analysis,ACT scores were negatively correlated with SAS and SDS scores（ r =- 0. 51 /- 0. 19,t =- 7. 22 /- 3. 18）（ P〈0. 05）. Conclusion Compared with Group 2,observation group is potential easy to have anxiety / depression; compared with Group 1,observation group is easier to have anxiety / depression. The anxiety / depression degree is closely correlated with control effects of asthma. The higher the degree of anxiety / depression is,the poorer the control effect of asthma is.