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HIV/AIDS 相关淋巴瘤研究进展 被引量:2

Research progress of HIV/AIDS related lymphoma
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摘要 人类免疫缺陷病毒(HIV)/获得性免疫缺陷综合征(AIDS)相关淋巴瘤(ARL)是一组异质性肿瘤,预后较差。近年来阐明的发病机制包括 HIV 引起的免疫损伤、EB 病毒的感染及基因的改变。ARL 的病理类型主要有4种,即弥漫大 B 细胞淋巴瘤、Burkitt 淋巴瘤、原发渗出性淋巴瘤和浆母细胞淋巴瘤。形态学特征、免疫标记和遗传学特点的联合应用有助于诊断和鉴别诊断,从而有利于及时治疗和改善预后。 HIV /AIDS related lymphoma (ARL)are a group of heterogeneity of neoplasms,and they have poor prognosis.The factors of pathogenesis elucidated in recent years include immune injury caused by HIV,EB virus infection and genetic changes.There are four pathological types of ARL,including diffuse large B cell lymphoma,Burkitt lymphoma,plasmablastic lymphoma and primary effusion lymphoma.Morphological characteristics,immunophenotype markers and clinical data should be combined to make diagnosis and differential diagnosis,which will facilitate timely treatment and improve prognosis.
作者 王迪 冯艳玲
出处 《国际肿瘤学杂志》 CAS 2015年第6期475-477,共3页 Journal of International Oncology
关键词 HIV 感染 淋巴瘤 肿瘤形成过程 病理学 HIV infections Lymphoma Neoplastic processes Pathology
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参考文献22

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