贮存式自体输血在人工髋关节置换术中的安全性研究

Safety of transfusion with stored autologous blood in artificial hip replacement

目的观察贮存式自体输血在人工髋关节置换术中的临床效果,探讨在人工髋关节置换术中实施贮存式自体输血对患者安全的影响。方法收集采用贮存式自体输血的50例人工髋关节置换术患者为观察组,采用异体输血的50例患者为对照组,观察两组患者手术前后血常规、血电解质及围术期恢复情况。结果观察组患者手术前后血常规、血电解质指标未出现明显变化(P>0.05),其中发生肺炎1例,高热1例,住院时间(6.5±1.7)d。对照组患者手术后血常规指标明显低于手术前,血电解质指标中血钾高于术前,血钙低于术前(P<0.05或0.01),术后出现高热5例,肺炎3例,泌尿道感染3例,住院时间(9.8±3.8)d,两组患者输血后感染率和住院时间比较,差异有统计学意义(P<0.05)。结论贮存式自体输血科学安全、经济有效,减少患者异体输血并发症,节约血源,可广泛应用于人工髋关节置换术等择期手术。

Objective To evaluate the safety of transfusion with stored autologous blood in in artificial hip replacement. Methods One hundred patients underwent artificial hip replacement surgery from June 2011 to June 2014, among whom 50 cas-es receive stored autologous blood transfusion （test group） and 50 received al ogeneic blood transfusion （control group）. Preop-erative and postoperative blood routine, electrolytes, and perioperative recovery were compared between two groups. Results There were no significant changes in blood routine and electrolytes of test group before and after surgery（P〉0.05）, while in con-trol group the blood routine indicators and blood calcium were lower and blood potassium was higher after surgery than those before surgery （P〈0.05 or 0.01）. In test group there was 1 case of pneumonia and 1 case of high fever, while in control group there were 3 cases of pneumonia, 5 cases of high fever and 3 cases of urinary tract infection. The length of hospital stay in test group was shorter than that in control group （6.5±1.7d vs 9.8±3.8d, P〈0.05）. Conclusion Stored autologous blood transfusion is safe, economic and effective with less complications for patients undergoing elective artificial hip replacement.