5Mckeage K, Perry CM. Propofol :a review of its use intensive care sedation of adultes[J]. CNS Drugs, 2003, 17(4) :235.
6Boyer J . Treating agitation with dexmedetomidine in the ICU [J]. Dimens Crit Care Nurs, 2009, 28 (3) : 102-109.
7Martin E, Ramsay G, Mantz J, et al. The role of the alpha 2-ad- renoeeptor agonist dexmedetomidine in postsurgical sedation in the intensive care unit [ J ]. Intensive Care Med, 2003, 18 ( 3 ) 2941.
8Urban MK, Wukovits B, Flynn E. Dexmedetomidine versus propofol for sedation of ventilated spinal patients[J]. Anesthe- siology, 2004,101 (3) -158.
9Taniguchi T, Kidani Y, Kanakura H, et al. Effects of dexme detomidine on mortality rate and inflammatory responses to en dotoxin induced shock in rats [J]. Critical Care Medicine, 2004, 32(5) :1322-1326.
10Mantz J. Alpha 2-adrenoceptor agonists analgesia, sedation anxiolysis,haemodyrmmics, respiratory function and weanir [ J ]. dlliere "s ClinAnaesthesiol ,2000,14(2) : 443448.
3Buckingham JC.Hypothalamo-pituitary responses to travma[J].Br Med Bull;1985(41):203-211.
4Angst MS,Ramaswamy B,Dav ies F,et al.Comparative analgesic and mental effects of incerasing plasma concentrations of dexmedetomidine and alfentanil in humans[J].Anesthesiology;2004(1):744-52.
5Dyck JB,Maze M,Haack C,Vuorilehto L,et al.The pharmacokinetics and hemodynamic effects of intravenous and intramuscular dexmedetomidine hydrochloride in adult human volunteers[J].Anesthesiology;1993(78):813-20.
6Kuzucuo lu T,B lükba o lu I,Arslan G,et al.Comparison of the activity and reliability of intravenous administration of midazolam and dexmedetomidine on sedation levels under epidural anesthesia[J].Agri,2010(22):121-30.
7Terao Y,Ichinomiya T,Higashijima U,et al.Comparison between propofol and dexmedetomidine in postoperative sedation after cervical spine surgery[J].J Anesth;2011,dec.16:DOI 10,1007/s00450-011-1300-7.
