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纪念“结晶胰岛素全合成”50周年——后继工作之一:单、双链胰岛素的体外折叠 被引量:1

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摘要 在胰岛素合成中,在A链内和A、B链间的3对二硫键正确配对是合成成功的关键。
作者 冯佑民
出处 《生命科学》 CSCD 2015年第6期686-689,共4页 Chinese Bulletin of Life Sciences
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  • 1[5]Katsoyannis P G.,Tometsko A,Zalut C.Insulin peptides.Ⅶ.Human insulin generation by combination of synthetic A and B chains.J Am Chem Soc,1966,88:166-167
  • 2[6]Zahn H,Brinkhoff O,Meienhofer J,et al.Combining of synthetic insulin chains into biologically active preparation.Z Naturforsch B,1965,20:666-670
  • 3[7]Dixon G H,Wardlaw A C.Regeneration of insulin activity from the separated and inactive A and B chains.Nature,1960,188:721-724
  • 4[8]Du Y C,Zhang Y S,Lu Z X,et al.Resynthesis of insulin from its glycyl and phenylalanyl chains.Sci Sin,1961,10:84-104
  • 5[9]Jiang R Q,Du Y C,Tsou C L.Further increase in the activity regenerated in the resynthesis of insulin from its glycyl and phenylalanyl chains.Sci Sin,1963,12:452-454
  • 6[10]Katsoyannis PG,Tometsko A.Insulin synthesis by recombination of A and B chains:A highly efficient method.Proc Natl Acad Sci USA,1966,55:1554-1561
  • 7[11]Chang J Y.A two-stage mechanism for the reductive unfolding of disulfide-containing proteins.J Biol Chem,1997,272:69-75
  • 8[12]Jiang C,Chang J Y.Unfolding and breakdown of insulin in the presence of endogenous thiols.FEBS Lett,2005,579:3927-3931
  • 9[13]Tang J G.,Tsou C L.The insulin A and B chains contain structural information for the formation of the native molecule:Studies with protein disulphide-isomerase.Biochem J,1990,268:429-425
  • 10[14]Wei J,Xie L,Lin Y Z,et al.The pairing of the separated A and B chains of insulin and its derivatives:FTIR studies.Biochim Biophys Acta,1992,1120:69-74

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