Embosphere微球联合碘油化疗栓塞治疗巨块型肝癌的临床疗效分析

Clinical studyof Embosphere microspheres combined with lipiodol chemoembolization for the treatment of massive hepatocellular carcinoma

目的:研究Embosphere微球联合碘油化疗栓塞治疗巨块型肝癌的临床疗效。方法:30例巨块型肝癌患者,股动脉穿刺插管,行肝动脉造影,明确肿瘤的供血动脉后超选择插管,以Embosphere微球联合碘油化疗进行栓塞治疗。随访一年。结果:15例患者行1次治疗,8例患者行2次治疗,3例患者行3次治疗,4例患者行3次以上治疗。24例患者病情稳定,2例AFP在100μg/L左右波动,2例患者于发现病变后9个月、12个月死亡,2例患者病变进展。结论:Embosphere微球联合碘油化疗栓塞治疗巨块型肝癌疗效确切,患者肝硬化等基础疾病及病灶的大小是影响疗效的主要因素,治疗后的获益是肯定的。

Objective： Clinical studyof Embosphere microspheres combined with lipiodo｜ chemoembolization for the treatment of massive hepatocellular carcinoma. Methods：30 cases of massive hepatoeaUular carclnoma, Femoral artery puncture, Hepatic artery angiography. Clear tumor feeding artery after superselective catheterization, Embolization treatment with Embosphere microspheres combined with lipiodo[ chemotherapy. One year follow - up. Result： 15patients received one treatment, 8 patients underwent 2 times of treatment, 3 patients underwent 3 times of treatment, 4 patients underwent 3 or more treatment. 24 patients had stable disease; 2 eases of AFP wave in the 100 g/L; 2 patients were found lesions in 9 months after the death of 12 months;2 cases of patients with disease progression. Conclusion： Embosphere microspheres combined with lipiodol chemoembolization exact curative effect in the treatment of massive hepatoeeUular carcinoma, The basis of disease in patients with cirrhosis of the liver and the size of the lesion is the main factors influencing the curative effect, After treatment, the benefit is in the affirmative.