宫颈细胞学结果与阴道微生态相关性研究

Study on correlation between Cervical cytology and vaginal microflora

目的通过对宫颈细胞学的阴道微生态研究,揭示宫颈病变的发病原因,为治疗和预防宫颈病变提供依据。方法对4 630例正常健康妇女进行常规白带及宫颈细胞学检查(其中TCT 3 643人,宫颈刮片987人)。结果宫颈细胞学检查结果:宫颈细胞学正常组阴道微生态失调309人,占该组的11.66%;宫颈细胞学反应性改变的轻度炎症组:阴道微生态失调563人(563/1 689),占该组的33.33%;鳞状上皮异常组:阴道微生态失调59人,占该组人数的78.67%(59/75),正常组的微生态失调与反应性改变组、鳞状上皮异常组的微生态失调,三者间比较均有统计学意义(P<0.001),且宫颈炎症的加重程度与阴道微生态失调的比率呈正比。结论宫颈病变与阴道微生态失调有密切关系。

Objective Through the vagina micro ecology study of cervical cytology, reveal the etiology of cervical lesion, provide the basis for the treatment and prevention of cervical lesions. Methods In 4630 cases of normal healthy women to normal leucorrhea and cervical cytology examination （including TCT3643, cervical smear, 987）. Results Cervical cytology results normal group and reactive change group, squamous epithelium abnormalities were vaginal micro- ecological imbalance in situation, the comparison between the three had statistical significance （ P 〈 0. 001 ）, and the deterioration of the cervical inflammation degree and the ratio of vaginal microecological imbalance was positively. Conclusion There is a close relationship between pathological changes of cervical and vaginal mieroecological imbalance.