维持性血液透析伴HCV感染患者的护理干预对丙肝治愈率的影响

Effects of targeted nursing intervention on the cure rate of hepatitis C in maintenance hemodialysis patients with HCV infections

目的 探究采取针对性护理干预措施对维持性血液透析伴HCV感染患者丙肝治愈率影响,为提高临床护理质量提供指导.方法 选用自2010年1月就诊的维持性血液透析伴HCV感染患者11例,治疗期间采用干扰素皮下注射治疗6个月,治疗过程中采用针对性护理干预治疗措施,分析治疗期间和治疗后6个月丙肝治愈率和并发症状况.结果 11例维持性血液透析伴HCV感染患者除有1例产生严重副作用退出研究,其余10例均通过6个月治疗过程,治疗结束后,检测血清ALT在40U/1以下,血清HCV-RNA呈阴性,在随访后6个月,10例患者血清ALT在40U/1以下,血清HCV-RNA呈阴性.结论 对维持性血液透析伴HCV感染患者干扰素救治过程中采用针对性护理干预措施能显著提高患者丙肝治愈率并降低其并发症,值得临床推广.

Objective To explore the effect of targeted nursing intervention measures on the cure rate of hepatitis C in maintenance hemodialysis patients with HCV infections,so as to provide rational guidance in nursing quality improvement.Methods Eleven HCV infected patients who were receiving hemodialysis in our hospital on January 2010 were recruited as research subjects.All patients were subcutaneously injected with interferon for 6 months and were given individualized nursing measures during hemodialysis.Cure rates of hepatitis C and complications during the treatment and within 6 months after treatment were analyzed.Results Ten cases out of 11 maintenance hemodialysis patients with HCV infection finished 6 months treatment,only 1 cases was excluded from the study because of serious side effects and their serum ALT levels were below 40U/l and HCV-RNAs were negative.For the 10 patients,serum ALT was still below 40U/l and HCV-RNA remained negative over the 6 months after treatment.Conclusions Targeted nursing interventions can improve the cure rate and reduce the complications of HCV infections for maintenance hemodialysis patients with hepatitis C.