魔芋葡甘聚糖对小鼠的防醉解酒作用

Study on the effect of konjac glucomannan on preventing drunkenness and relieving alcoholism of mice

目的:以乙醇致醉的醉酒小鼠为对象,研究魔芋葡甘聚糖(KGM)对小鼠的防醉解酒作用。方法:通过解酒、防醉、攀附、检测小鼠全血乙醇含量的实验,探究KGM对小鼠的防醉解酒作用。结果:魔芋葡甘聚糖可显著(p<0.05)延长小鼠对酒精的耐受时间,缩短醉酒的维持时间。在小鼠全血乙醇含量检测中,醉酒小鼠血液乙醇高峰在酒后60min出现,且中、高KGM组较模型组乙醇浓度显著(p<0.05)缩小,因此KGM可明显降低醉酒小鼠血液中乙醇浓度。结论:魔芋葡甘聚糖具有良好的解酒防醉效果。

objective：The study aimed to discuss the effect of konjac glucomannan on preventing drunkenness and relieving alcoholism of mice. Methods：The effect of konjac gluconannan on preventing drunkenness and relieving alcoholism of mice was explored through the methods of preventing alcoholism and relieving alcoholism and clings,and detecting the ethanol concentration in the blood of the drunken mice. Results：The konjac gluconannan could significantly（p〈0.05） postpone the tolerance time of mice to the alcohol,and shorten the duration of drunkenness obviously. Depending on the results of detecting the ethanol concentration in the blood of the drunken mice,the ethanol concentration peak of the drunken mice appeared around 60min,and the ethanol concentration of the middle and high dose KGM group was significantly（p〈0.05） lower than the model group. So konjac glucomannan could decrease the ethanol concentration in the blood of the drunken mice significantly. Conclusion：The konjac gluconannan had good effects on preventing drunkenness and relieving alcoholism.