情绪和认知功能对早期脑梗死患者运动功能影响的研究

Affect of mood and cognitive function on motor function in patients with acute cerebral infarction

目的：研究脑梗死患者早期运动功能障碍与认知功能和情绪之间的关系。方法：收集自2011年5月～2014年5月于我院就诊的脑梗死患者78例，用上肢功能评定表（ DASH）、10m步行速度、认知评估量表（ MoCA）、焦虑自评量表（ SAS）、抑郁自评量表（ SDS）进行评定；比较患者弥散张量成像（ DTI）相关参数：各向异性分数（ FA）值、表观扩散系数（ ADC）和FA指数、ADC指数，并与认知和情绪评估结果进行相关性分析。结果：DASH评分和10m步行速度与MoCA、SAS、SDS评分无相关性（ P＞0．05）；患侧和健侧内囊后肢的FA值均与SDS评分呈负相关（P＜0．05）。结论：脑梗死患者早期运动障碍与情绪和认知功能无相关性，而梗死灶所致的神经网络缺损则与情绪相关。

Objective：To analyze the relationship between motor dysfunction with cognitive function and mood among patients with a-cute cerebral infarction. Methods：Collected 78 cases patients with cerebral infarction, use upper limb function assessment table （DASH）, 10m walking speed, Cognitive Assessment （MoCA）, Self -Rating Anxiety Scale （SAS）, Self -Rating Depression Scale （ SDS） to assess;comparison of patients with diffusion tensor imaging （ DTI） parameters：fractional anisotropy （ FA） values, and the ap-parent diffusion coefficient （ ADC） and FA index, ADC index, then correlation analysis and assessment of cognitive and emotional.Re-sults：DASH score and 10m walking speed had no correlation with MoCA, SAS, SDS scores （P〉0.05）;FA values in the ipsilateral and contralateral handers were negatively correlated （P〈0.05） with SDS sorce.Conclusion：Cerebral infarction movement disorders might have no correlation with mood and cognitive function, while the infarct-induced defects in patients with neural networks should be associ-ated with emotions.