临床药师对稳定期慢性阻塞性肺疾病患者的用药指导

Medication guidance for patients with stable chronic obstructive pulmonary disease by clinical pharmacists

目的探讨临床药师在慢性阻塞性肺疾病(COPD)稳定期用药治疗中的作用。方法将我院2010年1月至2013年1月出院的COPD患者124例,完全随机分为对照组和干预组,于出院后1、3、6个月,应用BODE指数评价效果。结果第1个月,两组BODE指数比较差异无统计学意义(P>0.05);第3个月,干预组患者的BMI、FEV1%pred%等较对照组增加(P<0.05);第6个月,干预组的m MRC、6MWD较对照组降低(P<0.05)。结论临床药师参与稳定期COPD患者的药物指导,有利于提高患者的生活质量。

Objective To study the role of clinical pharmacists in the medication of stable chronic obstructive pulmonary disease（ COPD）. Methods One hundred and twenty-four patients with COPD in our hospital from January2010 to January 2013 were randomly divided into two groups： control group and intervention group. The intervention results were tested by BODE index evaluation test at 1,3,6 months after discharge. Results At the first month of intervention,there was no significant difference in BODE index between the two groups（ P〉0. 05）; at the third month,the BM I,FEV1% pred% in intervention group were higher than those of control group（ P〈0. 05）; at the sixth month,the m M RC and 6M WDS in intervention group were significantly lower than those of control group（ P〈0. 05）. Conclusion It is beneficial to the patient＇s quality of life that clinical pharmacists participated in the medication guidance for patients with stable COPD.