自拟前列癃闭通方联合非那雄胺治疗经尿道等离子前列腺剜除术后患者的临床观察

Clinical Curative Effect Observation of Self-made Qianlielongbitong Fang and Finasteride after PKEP

目的:观察中西医结合治疗经尿道等离子前列腺剜除术后患者相关症状的临床应用效果。方法:选择2014年1-12月在本院行经尿道等离子前列腺剜除术的肾虚瘀阻型患者60例,随机分为治疗组(n=30)和对照组(n=30)。治疗组围手术期口服自拟前列癃闭通方联合非那雄胺,对照组仅口服非那雄胺。比较两组术前、术后1周、2周国际前列腺症状(IPSS)、生活质量(QOL)评分及最大尿流率(Qmax)、血尿转阴情况。结果:两组术后l、2周前列腺症状评分、生活质量评分、尿流率均比术前有显著改善(P<0.05);术后第2周,两组前列腺症状评分比较差异具有统计学意义(P<0.05);而两组术后第1、2周血尿转阴情况无明显差异。结论:在经尿道等离子前列腺剜除术围手术期辅助辨证使用中药治疗,可明显改善术后下尿路症候群症状,且不增加术后迟发性出血的风险。

Objective：To observe the curative effect of combine traditional Chinese and Western medicine treatment on patients after PKRP.Method：60 suitable patients with kidney deficiency and blood stasis who were after PKRP operations from January 2014 to December 2014 were randomly divided into the treatment group（n=30）and the control group（n=30）.All patients were given corresponding treatment in perioperation period.Parameters included international prostate symptom score（IPSS）,quality of life score（QOL）,maximum urinary flow rates（Qmax）,and hematuria were observed before the operation and 1 week,2 weeks after the surgery.Result：Compared with the preoperative,IPSS,QOL,Qmax of two groups were significantly improved,the differences were statistically significant（P〈0.05）.But 2 weeks after the surgery,IPSS,QOL between the two groups had significant difference（P〈0.05）;however,hematuria,after operation there was no significant difference in both groups.Conclusion：In the perioperative auxiliary treatment using traditional Chinese medicine can not only significantly improve lowerurinary tract symptom（LUTS）after surgery,but also do not increase the risk of postoperative delayed hemorrhages.