Non-coding regions of the Ebola virus genome contain indispensable phylogenetic and evolutionary information 被引量：2

Non-coding regions of the Ebola virus genome contain indispensable phylogenetic and evolutionary information

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摘要 We compared the numbers of nucleotide substitutions occurring in the non-coding regions and coding regions of Ebola virus genomes and found that non-coding regions contain indispensable phylogenetic and evolutionary information. The omission of genetic data from non-coding regions can lead to unreliable phylogenies and inaccurate estimates of evolutionary parameters. We compared the numbers of nucleotide substitutions occurring in the non-coding regions and coding regions of Ebola virus genomes and found that non-coding regions contain indispensable phylogenetic and evolutionary information. The omission of genetic data from non-coding regions can lead to unreliable phylogenies and inaccurate estimates of evolutionary parameters.

作者 JIANG XinQuan ZHANG ZhenJie ZHUANG DongMing CARR Michael J. ZHANG RuiLing LV Qiang SHI WeiFeng

机构地区 School of Public Health Institute of Pathogen Biology National Virus Reference Laboratory

出处《Science China(Life Sciences)》 SCIE CAS CSCD 2015年第7期682-686,共5页 中国科学（生命科学英文版）

基金 supported by the National Natural Science Foundation of China(81470096) the Doctoral Starting up Foundation of Taishan Medical College supported by a grant from the International Development Research Centre

关键词 EBOV EBOLA non-coding region phylogenetic analysis evolutionary information 非编码区病毒基因组系统发育进化信息核苷酸替换参数估计基因数据

分类号 R373 [医药卫生—病原生物学]

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