应用周围神经松解术治疗糖尿病性周围神经病的疗效研究

Effect of peripheral neurolysis therapy on diabetic peripheral neuropathy

目的 探讨周围神经松解术在糖尿病性周围神经病的临床治疗效果. 方法 对2007—2011年收治的105例糖尿病性周围神经病患者资料进行分析, 根据不同手术治疗方案将患者分为对照组和观察组,对照组采用常规方法治疗,观察组实施周围神经松解术治疗,比较两组疗效. 结果 观察组创面愈合时间为（17.97±4.34） d、新鲜肉芽生长时间为（5.23±2.28） d、术后1个月VAS评分为（1.48±1.12）分,显著少于对照组（P〈0.05）;观察组术后49例愈合,51例疼痛缓解,43例皮肤触、温觉恢复,均多于对照组（P〈0.05）;观察组截肢、溃疡复发率为0%,低于对照组（26%）（P〈0.05）. 结论 糖尿病性周围神经病患者采用周围神经松解术治疗效果理想,值得临床推广应用.

Objective To investigate the clinical effect of peripheral nerve neurolysis in diabetic peripheral neuropathy. Methods 105 cases of diabetic peripheral neuropathy in patients were admitted to our hospital for analysis, depending on the surgical treatment patients were divided into a control group and the observation group, the control group used conventional methods of treatment, observation group used peripheral nerve neurolysis, compared two groups. Results The healing time was （17.97 ± 4.34） days, the fresh growth of granulation time was （5.23 ± 2.28） days VAS score was （1.48 ± 1.12） 1 month after operation, significantly less than the control group （P〈0.05）;49 cases of patients in the observation group healed, pain relief in 51 cases, 43 cases of skin touch, temperature sensation recovery, were more than the control group （P〈0.05）; in observation group amputation, ulcer recurrence rate was 0%, lower than the control group （26 %） （P〈0.05）. Conclusion Patients with diabetic peripheral neuropathy using the lax treatment of peripheral nerve neurolysis can obtain ideal effect, should be introduced.