雪诺酮治疗早孕期先兆流产的效果观察及护理

Nursing and effect of cyclogest in threatened abortion treatment

目的探讨阴道用雪诺酮凝胶治疗先兆流产的效果,并总结护理要点。方法将在本科室就诊确诊为早孕期先兆流产的孕妇42例,根据随机数字表法将孕妇随机分为对照组和试验组,每组各21例,对照组孕妇每天给予黄体酮油剂40 mg肌内注射,试验组孕妇每天给予雪诺酮90 mg阴道用药。治疗两周后,比较两组孕妇先兆流产症状改善情况、安胎成功率、人绒毛膜促性腺激素(human chorionic gonadotropin,HCG)和孕酮(progesterone,P)的变化情况。结果两组孕妇治疗后先兆流产症状情况、安胎成功率和HCG值比较,均P>0.05,差异无统计学意义;两组治疗后P值比较,P<0.001,差异具有统计学意义,对照组明显高于试验组。结论先兆流产孕妇阴道使用雪诺酮后血清P水平升高不如肌内注射黄体酮,但治疗先兆流产效果相当。护理方面向孕妇宣教黄体酮及雪诺酮的副作用及疗效,解除孕妇使用顾虑,并做好心理及不舒适症状、药物治疗护理工作。

Objective To explore the effect of cyclogest and femotroneinthreatened abortion treatment and summerize key points of nursing. Methods Forty-two cases of first trimester threatened abortion women were selected from department of gynecology and obstetrics, which were randomly divided into the control group （n=21） and experiment group （n=21）using random digit table. The control group was given femotrone 40mg intramuscular injection each day while the experiment group was given 90 mg of vaginal progesterone suppository （Cyclogest） each day. Compare the improvement of symptoms, the success rate of pregnancy, changes in serum human chorionic gonadotropin （HCG） and progesterone. Results The improvement of symptoms, curative effects and change of HCG of both groups were no significantly difference. But elevatorconcentration of serum progesterone in femotrone group was higher than that of the cyclogest groupwith statistically difference. Conclusions Although cyclogest cannot appear significantly in increasing serum progesterone levels, it has the same effect as femotrone. Recommendations and notes about the use and side effects of cyclogest and femotrone should be provided for education to alleviate concerns of patients.