从瘀论治畸形精子症的临床研究

Clinical study on treating teratospermia with blood stasis

目的探讨从瘀论治疗畸形精子症临床效果。方法选取我院2013年5月至2014年7月男科门诊就诊的不育症患者,经精子染色体涂片检测确诊为畸形精子症(正常形态精子<4%)者95例,随机分成两组,其中观察组55例,对照组40例。对照组采用左卡尼汀口服液和维生素E胶丸治疗,观察组采用血府逐瘀汤治疗,比较两组患者治疗后临床效果及患者满意度。结果观察组治疗有效率为96.36%明显高于对照组85.00%治疗总有效率,两组比较有统计学意义(P<0.05);观察组治疗后精子浓度和正常形态精子明显高于对照组,两组间各值比较有统计学意义(P<0.05);观察组患者治疗满意度为92.72%明显高于对照组77.50%治疗满意度,两组比较有统计学意义(P<0.05)。结论从瘀论治疗畸形精子可提高精子正常形态和浓度,提高受孕机率,具有显著治疗效果,值得在临床中推广应用。

Objective To investigate the clinical effect of blood stasis in the treatment of sperm deformity disease .Methods Infertility patients select from andrology outpatient department in our hospital during May 2013 and July 2014 were enrolled this study （n=95）, they were diagnosed as teratospermia （normal sperm morphology〈4%） through the sperm chromosome smears , and they were divided into observation group （ n =55 ） and control group （n=40） randomly.Control group adopt the levocarnitine oral solution and Vitamin E Soft Capsules for treatment, and patients in observation group adopt XuefuZhuyu decoction for treatment .Clinical effect and satisfaction of the two groups after treatment were compared .Results The effective rate of the treatment in observation group was （96.36%） apparently hiher than that of the control group （21.67%）, the sperm concentration and number of normal sperm morphology of the observation group was significantly higher than the control group, the satisfactory rate of the observation group was （ 92.72%） higher than the control group （77.50%）, the differences between the two groups were statistically significant （P〈0.05）.Conclusions It can improve sperm normal morphology and concentration under the treatment of abnormal sperm from blood stasis , improve the probability of pregnancy and is worthy of clinical application .