2005-2012年贵州省伤寒副伤寒监测分析

Typhoid and paratyphoid surveillance analysis of Guizhou province during 2005-2011

目的利用＂中国疾病监测信息报告管理系统＂及贵州省伤寒副伤寒国家级监测点上报的监测数据,分析贵州省伤寒副伤寒流行特征及监测中存在的问题。方法采用描述流行病学方法对贵州省2005-2012年伤寒副伤寒病例和监测点监测数据资料进行分析。结果贵州省伤寒副伤寒发病死亡呈下降趋势,发病以农民和学生为主,发病高峰为5~9月;全省2个监测点2005-2012年共采集4 578份标本,伤寒副伤寒杆菌总的阳性检出率为6.47%（296/4578）,病原菌型监测显示伤寒菌占18.24%（54/296）、副伤寒杆菌占81.76%（242/296）,伤寒副伤寒菌耐药情况较为普遍,菌株对氨苄西林、阿莫西林/棒酸等药物敏感。结论 ＂中国疾病预防控制信息系统＂和国家级伤寒副伤寒监测点的主动监测可相互补充,对指导贵州省伤寒副伤寒防控有积极意义。

Objective By using the surveillance data obtained from National diseaze reporting information sys- tem, to analyze the problems in surveillance of the epidemic pattern of typhoid and paratyphoid in Guizhou Province. Methods Descriptive epidemiological method analysis was conducted for typhoid and paratyphoid ca- ses and surveillance data of Guizhou province during 2005 -2012. Results The morbidity and mortality of ty- phoid and paratyphoid showed decline tendency in Guizhou province, the cases were mainly farmers and students, the incidence peak was during May - September; Total collected 4578 samples in 2 monitoring site in Guizhou province, the total positive rate of typhoid and paratyphoid bacillus was 6.47 % （296/4578）, pathogen type surveillance showed that typhoid bacillus accounted for 18.24% （54/296）, paratyphoid bacil- lus accounted for 81.76 % （242/296）, the drug - resistance of typhoid and paratyphoid bacillus was com- mon, bacterial strains were sensitive to Ampicillin, amoxicillin/ clavulanic acid and so on. Conclusions Na- tional disease reporting information system and active surveillance in national surveillance sites of bacillary dys- entery can provide more accurate information about the disease situation, which could facilitate the prevention and control of tvohoid and oaratvohoid.