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结核感染T细胞斑点试验对结缔组织病患者结核感染的诊断效果 被引量:7

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摘要 目的探讨结核感染T细胞斑点试验(T-SPOT.TB)对结缔组织病(CTD)合并结核感染的临床诊断价值。方法选取CTD合并结核感染患者58例,随机选取CTD患者60例作为对照,评估T-SPOT.TB和结核菌素皮肤试验(TST)对CTD合并结核感染患者的诊断价值。结果 T-SPOT.TB诊断CTD合并结核感染的灵敏度为75.86%,显著高于TST试验(31.03%)(P<0.05);T-SPOT.TB试验的灵敏度、特异度、阳性预测值、阴性预测值、约登指数、符合率等明显高于TST试验,而假阳性率和假阴性率明显低于TST试验;当T-SPOT.TB斑点形成细胞频数为30 SFCs/106PBMC时,诊断CTD合并结核感染的灵敏度和特异度均达到最高值,灵敏度为85.00%,特异度为74.14%(P<0.00001)。结论 T-SPOT.TB对CTD合并结核感染的临床诊断价值较高,明显优于TST试验。
作者 魏影
出处 《安徽医药》 CAS 2015年第7期1327-1329,共3页 Anhui Medical and Pharmaceutical Journal
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