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早期补救ICSI的实用性研究 被引量:1

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摘要 授精失败是指卵细胞不授精或受精率低下(授精的卵子个数小于 MⅡ卵子总数的30%)是 IVF 实验室中常见的难题,发生概率5%~10%[1]。此情况多见于原发不孕5年以上的患者,患者由此可能被迫放弃此次周期治疗,给患者带来巨大的经济和心理负担。而及时进行早期补救 ICSI 是避免授精失败的重要方法之一[2]。
出处 《实用医学杂志》 CAS 北大核心 2015年第12期2067-2068,共2页 The Journal of Practical Medicine
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  • 1李晓虹,于丛一,麦美琪,李予,苏宁,魏春霞,陈静华,杨冬梓,张清学.常规IVF不受精周期行补救卵母细胞单精子注射[J].中山大学学报(医学科学版),2007,28(2):188-191. 被引量:28
  • 2Kuczyflski W, Dhont M, Grygoruk C, et al. Rescue ICSI of unfertilized oocytes after IVF[J]. Hum Reprod, 2002,17 : 2423- 2427.
  • 3Chen C, Kattera S. Rescue ICSI of oocytes that failed to extrude the second polar body 6 h post-insemination in conventional IVF[J]. Hum Reprod,. 2003,18:2118-2121.
  • 4Nagy ZP, Rienzi LF, Ubaldi FM, et al. Effect of reduced oocyte aging on the outcome of rescue intracytoplasmie sperm injectio[J]. Ferti Steril, 2006,85 : 901-906.
  • 5Lipitz S, Rabinovici J, Goldenberg M, et al. Complete failure of fertilization in couples with mechanical infertility: implica- tions for subsequent cycles. Fertil Steril, 1994, 61(5):863-6.
  • 6Gurgan T, Urman B, Yarali H, et al. The results of in vitro fertilization-embryo transfer in couples with unexplained infertility failing to conceive with superovulation and intrauterine insemination. Fertil Steril, 1995, 64(1):93-7.
  • 7Dumoulin J, Coonen E, Bras M, et al. Embryo development and chromosomal anomalies after ICSI: effect of the injec- tion procedure. Hum Reprod, 2001, 16(2):306-12.
  • 8Wen J, Jiang J, Ding C, et al. Birth defects in children conceived by in vitro fertilization and intracytoplasmic sperm injection: a meta-analysis. Fertil Steril, 2012, 97(6): 1331-7.
  • 9Kuczynski W, Dhont M, Grygoruk C, et al. Rescue ICSI of unfertilized oocytes after IVF. Hum Reprod, 2002, 17(9): 2423-7.
  • 10Chen C, Kattera S. Rescue ICSI ofoocytes that failed to extrude the second polar body 6 h post-insemination in conventional IVF. Hum Reprod, 2003, 18(10):2118-21.

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