期刊文献+

磷酸西格列汀联合胰岛素治疗2型糖尿病效果观察 被引量:6

下载PDF
导出
摘要 目的:研究分析磷酸西格列汀联合胰岛素治疗2型糖尿病效果。方法:选取96例2型糖尿病患者进行回顾性分析,将其分为两组。其中观察组52例患者,采用地特胰岛素皮下注射联合磷酸西格列汀早餐前口服治疗;对照组44例患者,采用诺和灵30R皮下注射联合磷酸西格列汀早餐前口服治疗。结果:两组FPG、2h PG、HBAlc水平较治疗前显著降低,观察组2h PG含量明显低于对照组,治疗结束时,观察组胰岛素用量非常显著少于对照组,差异均有统计学意义(P<0.05)。结论:磷酸西格列汀联合地特胰岛素治疗2型糖尿病的效果显著,并能够较好地对血糖的含量进行控制,减少血糖波动,发生低血糖的风险降低,安全性更好,值得临床进一步推广。
作者 时庆平
出处 《吉林医学》 CAS 2015年第14期3128-3128,共1页 Jilin Medical Journal
  • 相关文献

参考文献4

二级参考文献49

  • 1Mohan V, Yang Wenying, Son HY, et al. Efficacy and safety of sitagliptin in the treatment of patients with type 2 diabetes in China, India, and Korea [ J ]. Diabetes Res Clin Pract ,2009,83 ( 1 ) : 106 - 116.
  • 2Aschner P, Katzeff HL, Guo H, et al. Efficacy and safety of monotherapy of sitagliptin compared with metformin in patients with type 2 diabetes [ J]. Diabetes Obes Metab, 2010,12(1) :1 - 10.
  • 3Iwamoto Y, Tajima N, Kadowaki T,et al. Efficacy and safety of sitagliptin monotherapy compared with voglibose in Japa- nese patients with type 2 diabetes: a randomized, double-blind trial [ J ]. Diabetes Obes Metab, 2010, 12 ( 7 ) : 613 - 622.
  • 4Nonaka K, Kakikawa T, Sato A, et al. Efficacy and safety of sitagliptin monotherapy in Japanese patients with type 2 diabetes[ J ]. Diabetes Res Clin Pract, 2008,79 ( 2 ) : 291 - 298.
  • 5Herman DW, Round E, Swern AS,et al. Safety and tolera- bility of sitagliptin in patients with type 2 diabetes : a pooled analysis [ J ]. BMC Endocr Disord ,2008,8 ( 1 ) : 14.
  • 6Herman DW, Johnson J, Teng R,et al. Efficacy and safety of initial combination therap-y with sitagliptin and metform- in in patients with type 2 diabetes : a 54-week study [ J ]. Curr Med Res Opin,2009,25 (3) :569 - 583.
  • 7Herman DW, Johnson J, Teng R,et al. Efficacy and safety of sitagliptin and mefformin as initial combination therapy and as monotherapy over 2 years in patients with type 2 diabetes [ J ]. Diabetes Obes Metab,2010,12(5):442-451.
  • 8VilsOll T, Rosenstock J, Yki-Jarvinen H, et al. Efficacy and safety of sitagliptin when added to insulin therapy in patients with type 2 diabetes [ J ]. Diabetes Obes Metab, 2010,12(2) :167 - 177.
  • 9Raz I, Chen Yu, Wu Mei,et al. Efficacy and safety of sita- gliptin added to ongoing metfor-min therapy in patients with type 2 diabetes[J]. Curr Med Res,2008,24(2) :537 -550.
  • 10Scott R, Loeys T, Davies MJ,et al. Efficacy and safety of sitagliptin when added to on-going metformin therapy in patients with type 2 diabetes [ J]. Diabetes Obes Metab, 2008,10(10) :959 - 969.

共引文献46

同被引文献42

引证文献6

二级引证文献12

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部