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利拉鲁肽治疗超重或肥胖的2型糖尿病患者疗效观察 被引量:7

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摘要 目的:观察利拉鲁肽在超重或肥胖的2型糖尿患者中的疗效。方法:筛选28例符合入选标准的超重或肥胖的2型糖尿患者,在口服降糖药物基础上,同时皮下注射利拉鲁肽0.6-1.8mg,1次/d。临床观察3个月,记录治疗前后空腹血糖(FPG)、餐后2h血糖(2h PG)、糖化血红蛋白(HBA1C)、体重、C肽的变化情况并进行比较。观察并记录其不良反应。结果:对采利拉鲁肽治疗后患者的空腹血糖、餐后2h血糖、糖化血红蛋白及体重均降低,而C肽水平升高,其差异有统计学意义(P〈0.05)。观察到部分患者出现不良反应,但能耐受治疗。结论:在原有口服降糖药物基础上加用利拉鲁肽能有效降低血糖,减轻体重,减少低血糖,保护胰岛β细胞功能。
出处 《河北医学》 CAS 2015年第10期1707-1709,共3页 Hebei Medicine
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