医源性多胎妊娠原因与防治

Essentials to reduce iatrogenic multifetal pregnancy

医源性多胎妊娠(IMP)是指经医疗干预而获得的多胎妊娠。随着辅助生殖技术(ART)的发展,其发生率明显升高。IMP与控制性卵巢刺激的应用及向宫腔内移植多个胚胎有直接关系。多胎妊娠妇女各系统负担加重,妊娠期母儿并发症发生率高、病情重,减胎术是改善妊娠结局的主要手段。从根本上讲,IMP重在预防,应严格掌握超排卵治疗的指征、严格掌握排卵诱导药物的使用和控制移植胚胎数目。

Iatrogenic multiple pregnancy （IMP） refers to multiple pregnancy obtained by medical intervention. With the development of assisted reproductive technology （ART）, the incidence of IMP increased.Control ovarian stimulation and multiple embryo transfer are main risk factors of IMP.It increases the maternal burden and perinatal complication rate.Muhifetal reduction is the main remedial measure.The prevention of IMP is the most important task,and we should strictly control the indication of ovulation induction and ovarian hyperstimulation,drug use,and control the number of embryos transfer.