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卵巢早衰的生育治疗策略 被引量：6

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摘要 卵巢早衰(POF)病人的生育能力是其治疗难点,针对发病率高的特发性和化疗损伤性的卵巢早衰进行早期干预可增加生育机会。对于特发性POF引起的无排卵性不孕,不建议使用诱导排卵药物,采用基础窦状卵泡计数(AFC)等预测卵巢功能,积极监测人工周期,使用捐赠的卵母细胞体外受精(IVF)是可行的治疗选择。对女性肿瘤病人,可选择化疗前紧急辅助生殖或者化疗前及化疗期间采用冷冻卵巢组织、卵母细胞或胚胎,化疗结束后移植回体内等方案。
作者 顾超 孙晓溪 李斌
机构地区 复旦大学附属妇产科医院妇科 上海集爱遗传与不育诊疗中心
出处 《中国实用妇科与产科杂志》 CAS CSCD 北大核心 2015年第7期676-678,共3页 Chinese Journal of Practical Gynecology and Obstetrics
关键词 特发性卵巢早衰 化疗 生育能力 冷冻保存 idiopathic premature ovarian failure chemotherapy fertility cryopreservation
分类号 R711.75 [医药卫生—妇产科学]
  • 相关文献

参考文献23

  • 1Simpson JL. Genetic and phenotypic heterogeneity in ovarian failure : overview of selected candidate genes [J ]. Ann NY Acad Sci, 2008, 1135 : 146-154.
  • 2Persani L, Rossetti R, Cacciatore C. Genes involved in human premature ovarian failure [J]. Mol Endocrinol, 2010, 45 (5) : 257-279.
  • 3Kalantaridou SN, Nelson LM. Premature ovarian failure is not premature menopause [J]. Ann N Y Acad Sci, 2000,900 (3) : 393-402.
  • 4Molina JR, Barton DL, Loprinzi CL. Chemotherapy-induced ovarian failure: manifestations and management [J]. Drug Saf, 2005,28(5) :401-416.
  • 5Hubayter ZR, Popat V, Vanderhoof VH, et al. A prospective eval- uation of antral follicle function in women with 46, XX spontane- ous primary ovarian insufficiency [Jl. Fertil Steril, 2010, 94: 1769-1774.
  • 6Michael P, David A, Rossi G, et al. Counter-regulatory response to hypoglycemia in the follicular and lutel phases of the menstru- al cycle[J]. Fertil Steril, 1993,59(5) :988.
  • 7Kalu E, Panay N. Spontaneous premature ovarian failure : man- agement challenge [J ]. Gynecol EndocrinoI, 2008,24 (5) : 273- 279.
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二级参考文献12

  • 1潘长穿,陈文卫,石华,杨菁,徐望明,孙有刚.经阴道彩色多普勒超声诊断卵巢早衰的研究[J].中国医学影像学杂志,2004,12(6):455-456. 被引量：22
  • 2金婧,阮祥燕.卵巢早衰的病因研究进展[J].实用妇产科杂志,2007,23(3):142-145. 被引量：57
  • 3Kalu E, Panay N. Spontaneous premature ovarian failure: management challenge[J]. Gynecol Endocrinol, 2008, 24(5): 273-9.
  • 4Nelson LM.Primary ovarian insufficiency[J]. N Engl J Med, 2009, 360(6): 606-14.
  • 5Frisch RE. Body fat, menarche, fimess and fertility [J]. Hum Reprod,1987, 2(6): 521-33.
  • 6Testa G, Chiaffarion F, Vegetti W, et al. Case-control study on risk factors for premature ovarian failure [J]. Gynecol Obstet Invest, 2001, 51(1): 40-3.
  • 7Progetto Menopause Italia Study Group. Premature ovarian failure:frequency and risk factors among women attending a network of menopause clinics in Italy[J]. BJOG, 2003, 110(1): 59-63.
  • 8Banesi LF, Broekmans FJ, Eijkemans MJ, et al. Predictors of poor ovarian response in in vitro fertilization: a prospective study comparing basal markers of ovarian reserve [J]. Fertil Steril, 2002, 77(2): 328-36.
  • 9Kalantaridou SN, Nelson LM. Premature ovarian failure is not premature menopause [J]. Ann N Y Acad Sci, 2000, 900(3): 393-402.
  • 10Michael P, David A, Rossi G, et al. Counter-regulatory response to hypoglycemia in the follicular and lutel phases of the menstrual cycle[J]. Fertil Steril,1993, 59(5): 988.

共引文献38

同被引文献56

引证文献6

二级引证文献61

中国实用妇科与产科杂志
2015年 第7期

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