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利多卡因气管内表麻提高神经探测仪在甲状腺手术中应用的灵敏度 被引量:5

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摘要 目的:研究利多卡因气管内表麻能否抑制甲状腺手术的牵拉反应,提高神经探测仪灵敏度。方法:选择拟全麻下行甲状腺大部切除术患者60例,随机分为两组。Ⅰ组:对照组:通过气管导管向气道内注入0.9%生理盐水2.5 m L;Ⅱ组:治疗组:气道内注入2%利多卡因溶液2.5 m L。观察指标:探测仪信号、气道压力、气道峰压(Ppeak)、血压(BP)、心率(HR)。结果:(1)探测仪信号变化:Ⅰ组深部手术刺激,患者出现气道高压以及循环系统波动,追加肌松药后探测仪信号消失;Ⅱ组利多卡因表麻对探测仪信号无影响;(2)Ⅱ组Ppeak明显<Ⅰ组,且两组气道压力的差值(ΔP)有统计学差异(P<0.01);(3)Ⅱ组循环指标更稳定,组间有统计学差异(P<0.05);(4)Ⅱ组耐管时间相对延长,组间有统计学差异(P<0.05)。结论 :2%利多卡因气管内表麻可改善牵拉肿物、刺激气道造成的气道高压,延长耐管时间、减少肌松药用量,不影响喉返神经探测仪功能,维持循环系统稳定。
作者 冯姗姗 张锦
出处 《实用医学杂志》 CAS 北大核心 2015年第11期1842-1844,共3页 The Journal of Practical Medicine
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参考文献10

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二级参考文献11

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