用药教育对肾病综合征患者服用糖皮质激素效果的影响

Effects of patient education in nephrotic syndrome patients taking glucocorticoids

目的:评估药物教育对患者的自身疾病认识程度、用药依从性、不良反应发生率的影响。方法:应用SPSS 19.0软件进行统计分析。计量资料采用t检验比较组间差异。计数资料采用χ2检验。P<0.05有统计学差异。结果:干预组和对照组对于药物的基本掌握情况平均分分别为(1.34±0.27)和(2.24±0.38),P<0.05,干预组为"了解"水平,对照组为"基本了解"水平。3个月内,干预组和对照组忘记服药次数为(0.30±0.65)和(1.23±1.54),P<0.05;发生感染的次数为(0.20±0.407),(0.70±1.159),P<0.05;第3个月内患者抽筋次数分别为(0.70±0.70),(8.55±11.46),P<0.05。结论:通过对长期服用糖皮质激素患者进行药学教育,可以显著提高患者对疾病药物的认识和用药依从性,减少药品不良反应的发生率。

Objective： To assess the effects of patient education on patients’ understanding of their own disease,medication compliance and the incidence of side effects. Methods： Spss19. 0 statistical analysis software was used. T test was used to compare the differences between the groups. The comparison between the count data was analyzed by Pearson χ2test. Results： The basic knowledge of medication was（ 1. 34 ± 0. 27） and（ 2. 24 ± 0. 38）（ P 〈 0. 05） in experimental and control groups. In three months,the numbers of forgetting to take medication were（ 0. 30 ± 0. 65） and（ 1. 23 ± 1. 54）（ P 〈 0. 05）,and the numbers of infection were（ 0. 20 ± 0. 407） and（ 0. 70 ±1. 159）（ P 〈 0. 05）. In the third month,the numbers of cramp were（ 0. 70 ± 0. 70） and（ 8. 55 ± 11. 46）（ P 〈0. 05）. Conclusion： Patient education is a good way to improve patients’ understanding of disease and medication compliance,and reduce the occurrence of adverse drug reactions in patients with long-term use of corticosteroids.