食管胃结合部腺癌行全胃与近端胃切除术临床分析

Clinical analysis of the total and proximal gastrectomy in the treatment of adenocarcinoma of the esophagogastric junction

目的:探讨食管胃结合部腺癌(AEG)行全胃切除术与近端胃切除术的疗效。方法:对43例进展期AEG患者随机分为全胃切除术(TG组)22例和近端胃切除术(PG组)21例。对2组患者的平均手术时间、术中失血量、住院时间、并发症的发生率、残胃癌综合征及术后1、2年生存率进行比较。结果:2组患者手术时间、术中失血量、住院时间、残胃癌综合征、术后并发症的发生率及1年生存率差异均无统计学意义(P>0.05);2年生存率差异有统计学意义(P<0.05)。结论:全胃切除术治疗进展期AEG,术后生存时间长,并发症发生率低,生活质量提高,可以作为治疗进展期AEG较理想的手术方式。

Objective：To investigate the therapeutic efficacy of the total and proximal gastrectomy in the treatment of adenocarcinoma of the esophagogastric junction（AEG）. Methods：Forty-three patients with advanced adenocarcinoma of the esophagogastric junction were randomly divided into the total gastrectomy group（ TG group,22 cases） and proximal gastrectomy group（ PG group,21 cases） . The average operation time, intraoperative blood loss, hospitalization time, incidence of complications, residual stomach syndrome and postoperative 1 and 2-year survival rates between two groups were compared. Results：The differences of the operation time, intraoperative blood loss,hospitalization time,incidence of complications,residual stomach syndrome and 1-year survival rate between two groups were not statistically significant（P〉0. 05）,the difference of the 2-year survival rate between two groups was statistically significant（ P〈 0. 05 ）. Conclusions：The total gastrectomy for treating the patients with advanced adenocarcinoma of the esophagogastric junction can increase their postoperative survival time,decrease their incidence of complications and improve their living quality,which is an ideal operation method.