丙种球蛋白在婴幼儿重症肺炎治疗中的疗效观察

The curative effect of gamma globulin in the treatment of severe pneumonia in infants

目的探讨静脉注射丙种球蛋白在治疗婴幼儿重症肺炎中的临床疗效。方法将80例重症肺炎患儿随机分为治疗组和对照组,各40例,两组患儿均进行常规治疗,治疗组则在此基础上加用丙种球蛋白400∽600 mg/（kg·d）,连用3∽5 d,比较两组患儿临床症状、体征消失的时间。结果治疗组与对照组相比,退热、喘鸣音消失、啰音消失、咳嗽症状消失时间及住院时间均明显缩短,疗效明显优于对照组,差异均具统计学意义（P均〈0.05）。结论加用丙种球蛋白治疗婴幼儿重症肺炎,能促进病情好转,提高治愈率,缩短治疗时间。

Objective To investigate the clinical efficacy of intravenous immunoglobulin in the treatment of severe pneumonia in infants. Methods The 80 cases of children with severe pneumonia were randomly divided into treatment group and control group with 40 cases in each. Two groups of children were conventional treatment, and the treatment group were given gamma globulin 400 - 600 mg/ （kg· d）, 3- 5 days, on the basis of this. Then we compared two groups of patients with clinical symptoms and signs disappeared time. Results By Comparison with the indexes of control group, fever, wheezing disappeared, rales, cough symptoms disappeared time and hospital stay of the treatment group were significantly shortened, and curative effect is obviously superior to the control group （P 〈 0.05）. Conclusion Combined with gamma globulin in the treatment of infants with severe pneumonia can promote better conditions, improve the cure rate and shorten the treatment time.