中孕期正常胎儿心血管系统结构超声测值的研究

Measurement of the normal fetal cardiovascular diameters by echocardiography during the second trimester in Ningxia

建立宁夏地区妊娠中期胎儿心血管系统各解剖结构内径的正常参考值范围,探求其随孕周变化规律。对妊娠中期（22～28周）正常胎儿1 246例行超声心动图检查,测量心房、心室、卵圆孔、主动脉、肺动脉、左/右肺动脉、主动脉弓峡部、降主动脉、动脉导管内径。根据孕周对测量数据进行分组,同时对各组测量数据和孕周进行相关性研究。胎儿心脏各房室及大血管内径随孕周增加而增大,与孕周显著相关（P〈0.05）。建立宁夏地区妊娠中期胎儿心血管系统结构相关的正常参考值范围,可评价胎儿心血管系统发育情况,为准确识别胎儿先天性心脏病提供重要依据。

To determine the normal range of the inner diameters of the anatomical structures in the fetal cardiovascular system during the second trimester in Ningxia and to investigate their variation with gestational age. Routine echocardiography was performed for 1 247 normal fetuses during the second trimester（22～28 weeks）to determine the inner diameters of the atrium,ventricle,foramen ovale,aorta,pulmonary artery,left/right pulmonary artery,aortic isthmus,descending aorta,and ductus arteriosus. Measurement data were grouped by gestational age,and the correlation between the measurement data and gestational age was investigated.The inner diameters of the fetal atria,ventricles,and great vessels increased with gestational age and were significantly associated with gestational age（P〈0.05）. In Ningxia,determining the normal range of fetal cardiovascular diameters during the second trimester allows the evaluation of fetal cardiovascular system development and provides an important basis for the accurate identification of fetal congenital heart disease.