人免疫球蛋白联合酚妥拉明治疗小儿重症肺炎的临床疗效观察

Observation on clinical curative effect of human immunoglobulin combined with phentolamine in the treatment of children with severe pneumonia

目的探讨人免疫球蛋白联合酚妥拉明治疗小儿重症肺炎的临床疗效。方法选择我院收治的重症肺炎患儿120例,将其分为观察组67例和对照组53例,对照组给予常规对症治疗,观察组在对照组基础上给予酚妥拉明以及人免疫球蛋白。结果观察组总有效率为95.52%显著高于对照组83.02%(P<0.05);观察组患儿气促消失时间、咳嗽消失时间、肺部啰音消失时间以及住院时间均显著短于对照组(P<0.05);治疗后,观察组Ig G水平较治疗前显著升高(P<0.05),且显著高于对照组(P<0.05);两组治疗期间均无明显不良反应。结论人免疫球蛋白联合酚妥拉明治疗小儿重症肺炎其临床疗效显著。

Objective To investigate the clinical efficacy of human immunoglobulin combined with phento-lamine in the treatment of children with severe pneumonia. Methods 120 children with severe pneumonia were ran-domly divided into the observation group （67 cases） and the control group （53 cases）. All patients were given rou-tine symptomatic treatment and phentolamine, and the observation group was additionally given human immunoglobu-lin. Results The total effective rate was 95. 52% in the observation group. which was significantly higher than that of the control group （83. 02% , P 〈 0. 05）. The time of shortness, cough and rales disappeared, and the duration of hospital stay were significantly shorter in the observation group than in the control group （P 〈 0. 05）. After the treat-ment, the level of IgG increased （P 〈 0. 05）, and it was significantly higher in the observation group than in the con-trol group （P 〈 0. 05）. There was no significant adverse reactions during treatment between the two groups. Conclu-sion Human immunoglobulin combined has significant curative effect in the treatment of children with severe pneu-monia.