吸烟者与非吸烟者的肺功能对比观察

Comparative observation of lung function between smokers and nonsmokers

目的探讨运用多排螺旋CT肺功能技术对吸烟者与非吸烟者的肺功能状态。方法选取100例吸烟者,作为研究组,并选取100例一般资料无显著差异的非吸烟者作为对照组。对两组的肺功能指标进行检测,并通过多排螺旋CT,检测两组主动脉弓、支气管分叉处吸气相和呼气相的PL-(900-950)、MLD的扫描值。结果与对照组对比,研究组用力呼气量占预计值百分比(FVC)、第一秒呼气容积占预计值百分比(FEV1)、第一秒呼气容积占用力呼气量百分比(FEV1/FVC)等肺功能指标明显低于对照组,差异有统计学意义(P<0.05)。在吸气相下,两组主动脉弓、支气管分叉处PL-(900-950)、MLD的扫描值相似,差异没有统计学意义(P>0.05)。在呼气相下,两组主动脉弓、支气管分叉处PL-(900-950)、MLD的扫描值具有明显差异,具有统计学意义(P<0.05)。结论非吸烟者的肺功能明显优于吸烟者,在呼气相下借助CT诊断,可为临床诊断治疗提供依据。

Objective To study the application of multiple row spiral CT pulmonary function technology to compare lung function between smokers and non-smokers. Methods The study selected 100 smokers as the experi- ment group and 100 non-smokers as the control group. Their lung function was detected by muhiple row helical CT, including aortic arch, bronchus divides inspiratory and expiratory phase of PL- （ 900 - 950） , and MLD. Results Compared with the control group, the value FVC, FEV1, and FEV1/FVC was significantly lower in the experiment group than in the controt group （P 〈0. 05）. The value of PL-（900 -950） and MLD showed no difference between the two groups under the inspiratory phase （ P 〉 0.05 ） , but it showed certain difference under the expiratory phase （P 〈 0. 05 ）. Conclusion The lung function of non-smokers is better than smokers, and it can provide the basis for clinical diagnosis and treatment under the expiratory phase by CT.