吸入糖皮质激素治疗儿童肺炎支原体肺炎的疗效观察

Observation on curative effect of glucocorticoid inhalation in the treatment of children with Mycoplasma pneumonia

目的观察布地奈德/氟替卡松序贯治疗儿童肺炎支原体肺炎的治疗效果。方法将60例患儿随机分为两组,基础治疗组予常规大环内酯类抗菌药治疗,吸入组在常规治疗上加用布地奈德/氟替卡松序贯治疗3月,比较两组疗效及病情反复情况。结果两组的咳嗽症状积分、发热和咳嗽的消失时间、住院时间以及反复次数,差异均有统计学意义(P<0.05)。结论吸入布地奈德/氟替卡松序贯治疗儿童肺炎支原体肺炎有助于缓解症状、缩短病程及减少病情反复。

Objective To observe the effect of sequential treatment of budesonide and Fluticasone on Myco- plasma pneumonia. Methods 60 children with Mycoplasma pneumonia were randomly divided into two groups. All children received macrolide anti-infection therapy, and the inhalation group was given sequential treatment of budes- onide and Fluticasone on the basis of conventional treatment for 3 months. The curative effect and recurrence of dis- ease were observed and compared between the two groups. Results The improvement of cough symptomatic scores, the disappear time of fever and cough, the duration of hospital stay and recurrence was more pronounced in the inha- lation group than in the control group. Conclusion Budesonide and Fluticasone can alleviate the symptoms, shorten the course of disease and reduce the relapse in the treatment of children with Mycoplasma pneumonia.