阿奇霉素注射液治疗儿童肺炎支原体肺炎68例疗效观察

Clinical observation of azithromycin injection in treatment of 68 children with mycoplasma pneumoniae pneu-monia

目的探讨分析阿奇霉素注射液治疗儿童肺炎支原体肺炎的临床疗效。方法将2012年5月至2014年4月在林州市妇幼保健院进行治疗的136例肺炎支原体肺炎患儿随机分为两组，治疗组68例，应用阿奇霉素治疗，对照组68例应用红霉素治疗。治疗后，比较两组疗效和不良反应以及两组症状消失时间等观察指标。结果经过治疗，治疗组总有效率为92．65％，高于对照组的79．41％，差异有统计学意义（P〈0．05）；治疗组咳嗽、发热以及肺部湿哆音等症状消失均少于对照组，肺部影像恢复时间和住院时间短于对照组，其不良反应发生率低于对照组，差异均有统计学意义（P〈0．05）。结论阿奇霉素注射液治疗儿童肺炎支原体肺炎的·临床疗效显著，具有推广价值。

Objective To investigate the clinical efficacy of azithromycin injection in treatment of children with mycoplasma pneumoniae pneumonia. Methods One hundred and thirty-six children with mycoplasma pneumoniae pneu- monia in maternal and child health care hospital of Linzhou from May 2012 to April 2014 were divided into two groups： the treatment group （68 cases） was treated by azithromycin injection and the control group （68 cases） was treated by erythro- mycin. After treatment, the curative effect, adverse reactions, symptoms disappear time and other indexes of two groups were analyzed. Results After treatment, the total effective rate of the treatment group （92. 65% ） was significantly higher than that of the control group （79. 41% , P 〈0.05）. The symptoms such as cough, fever, and lungs wet rale disappearing of the treatment group were less than the control group, pulmonary image recovery time and hospital stay was significantly less than that in the control group, and the incidence of adverse reactions was lower than that in the control group （P 〈 0. 05 ）. Conclusions The clinical efficacy of azithromycin injection on children with mycoplasma pneumoniae pneumonia is significant and worthy of being promoted.