我院2011-2013年抗菌药物应用管理成效分析

Analysis of Effects of Antimicrobial Drug Application Management in Our Hospital during 2011 to 2013

目的:巩固抗菌药物临床应用专项整治的成效,提高抗菌药物合理用药水平。方法:采用回顾性分析方法,对2011年(整治前和初期)、2012年(整治中期)及2013年(整治后期)的抗菌药物应用数据进行汇总对比分析。结果:专项整治前后(2011年1月与2013年12月比较),Ⅰ类切口围术期抗菌药物使用率由80.42%降至24.49%;急诊抗菌药物使用率由53.79%降至36.23%;住院患者特殊使用级抗菌药物微生物样本送检率由16.12%上升至94.17%;住院患者抗菌药物使用强度由70.28 DDDs/(100人·d)降至27.44 DDDs/(100人·d);住院患者抗菌药物使用率由65.99%降至46.45%。结论:我院实施专项整治的成效显著,但仍有持续改进的空间。

OBJECTIVE： To consolidate the results of special antibacterial drug rectification so as to improve the rational medi- cation of antibacterial drugs. METHODS： By using the method of retrospective analysis, the antibacterial drug application data in 2011 （before rectification and initial stage of rectification）, 2012 （middle stage thereof） and 2013 （later stage thereof） were sum- marized, compared and analyzed. RESULTS： After special rectification （Jan. 2011 vs. Dec. 2013）, the utilization rate of antibacte- rial drugs in perioperative period for class I incision decreased from 80.42% to 24.49%. That of antibacterial drugs in emergency treatment decreased from 53.79% to 36.23%. The examination rate of microbial samples in inpatients who would use special-grade antibacterial drugs increased from 16.12% to 94.17%. The use intensity of antibacterial drugs by inpatients decreased from 70.28 DDDs/（100 persons, d） to 27.44 DDDs/（100 persons-d）. The utilization rate of antibacterial drugs by inpatients decreased from 65.99% to 46.45%. CONCLUSIONS： Special rectification has remarkable effects on rational clinical application of antibacterial drugs. Regulation and evaluation should be strengthened to maintain the effects and continuously improvement should be made.