高血压住院患者经药物摄入钠的现状调查

Analysis of Sodium Intake via Drugs Used by Hypertensive Inpatients

目的:调查高血压患者住院期间经药物摄入钠的现状。方法:抽取2013年1-10月我院心血管内科高血压住院患者290例,对住院期间摄入含钠药物品种及钠摄入情况进行统计、分析。结果:275例高血压患者(94.8%)使用了38种含钠药物制剂,82.7%的医嘱采用了静脉滴注给药,平均使用含钠药物6.7 d(平均住院6.8 d),含钠溶剂如0.9%氯化钠注射液和注射用磷酸肌酸钠是主要的供钠药物;43.3%的患者摄入的药物钠超过了世界卫生组织(WHO)推荐的≤2 g标准。结论:高血压患者住院期间过多使用了含钠药物,临床上应尽量减少静脉给药和辅助性治疗药物来减少药物钠摄入,仅在患者预期获益大于风险时,方可开具含钠制剂处方。同时,药品生产企业应在药品说明书中注释其钠盐含量,方便医师抉择。

OBJECTIVE： To investigate sodium intake via drug used by hypertensive inpatients during hospitalization. METH- ODS： 290 inpatients with hypertension were collected from vasculocardiology department of our hospital between Jan. and Oct. 2013. The types of sodium-containing drugs and sodium-intake during hospitalization were analyzed statistically. RESULTS： 275 pa- tients with hypertension were prescribed 38 sodium-containing drugs （94.8%） ; 82.7% were administered by iv gtt with a average drug treatment course of 6.7 days （average hospitalization days of 6.8 days）. Solvent containing sodium such as 0.9% Sodium chlo- ride injection and Creatine phosphate sodium for injection were the most sodium donors. 43.3% patients＇ sodium intake exceeded upper limit of 2 g/day recommended by WHO. CONCLUSIONS： Hypertensive inpatients are prescribed too much sodium-contain- ing drugs, and less intravenous solutions and less adjuvant medicines should be took to decrease sodium intake. Only when prospec- tive benefit are greater than risk, the patients can be prescribed sodium-containing drug prescription.At the same time, manufacturers should annotate the content of sodium in package inserts, which is convenient for physicians to choose drugs.